Lucas Voss

He's the Principal Scientific Advisor at

at OrthoFix and brings more than 30 years of experience in pharmaceutical and medical device development.

He's a member of the American Academy of Orthopedic Surgeons and is widely recognized for his expertise in bone healing and bone growth therapies.

Dr. Rybie, welcome to the podcast.

It's so great to have you.

It's great to have you.

We have so much to talk about.

So much has happened in your field over the last couple of decades, I'd argue.

Again, you've been at the forefront of all of this, including a lot of the innovations that we've seen.

Looking back to the early days of bone growth stimulation, what first sparked interest in exploring the electrical and mechanical signals as therapeutic tools here?

Yeah, when you're describing it, it sounds really futuristic.

It's really a step forward for, and again, less invasive.

It gives people a chance to have better therapy.

And I want to touch on the technology piece of this a little bit more in detail, specifically pulsed electromagnetic field technology, or PEMF, as we might refer to it.

It's become an important approach in bone healing itself.

From your perspective, what were some of those key scientific or clinical milestones that help validate PMF as a credible evidence-based therapy?

You've touched on the ultrasound aspect of this as well, again, in the early days, and that this was essentially what was focused on in the ultrasound-based therapy, such as low-intensity pulse ultrasound introduced a different mechanism of action compared to PEMF.

How did the growing understanding of cellular signaling and bone biology influence the development of ultrasound-based bone healing technologies then?

Thank you so much for having me.

Earlier in our conversation, we've talked a little bit about the evolution of this and the evolution of these technologies and the development of them as well.