Luke O'Neill

speaker
138 appearances 1 recordings 1 series first heard Sep 2026 last heard 4d ago

Luke O'Neill’s voice in public audio — every appearance, attributed to the second.

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recordings per month · last 12 months
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Recordings per month over the last 12 months — 1 in all, peaking in Sep 2026 with 1.

Appearances

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All you're doing is you're you're decreasing the pathologic event of it, if you see what I mean.
Well, we we m men make it as well, Pat, right?
Let's put it that way.
So everybody can make this stuff in response to poisons or something in the diet.
You know, you will make GDF fifteen and you will vomit and have nausea, right?
And of course the big one, Pat, is chemotherapy.
And and as we all know, a big side effect there is severe nausea.
These drugs that you take for cancer, they're actually poisons in your body.
They're killing the tumour, of course.
But your body is making GDF fifteen to help sort of deal with the poison.
And nausea can be very debilitating.
And lo and behold, you block GDF fifteen in chemo and you decrease the nausea.
So the second big trial at the moment is block GDF fifteen on chemo.
And mercifully then there's less nausea in these people.
That'd be a huge benefit, obviously, to people.
And another benefit that
You've got it precisely.
That that's called cochexia.
And that's a very troubling symptom of cancer where muscle wasting happens.
And again, that's because you're making GDF fifteen in response to the chemo, you're nauseous, you're eating less.
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