Luke O'Neill

speaker

4,575 appearances 24 recordings 2 series first heard Apr 2026 last heard 3d ago

Luke O'Neill’s voice in public audio — every appearance, attributed to the second.

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recordings per month · last 12 months

Recordings per month over the last 12 months — 24 in all, peaking in Jul 2026 with 6.

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Show Me the Science with Luke O'Neill · The Science of Morning Sickness · 27 Aug 2026 podcast

It sounds stupid now, doesn't it? voice-verified

In the nineteen fifties, if you discovered a new drug for pregnant women, you didn't have to check if it was affecting development. voice-verified

Ever since the thalidomide disaster, you do have to. voice-verified

And by the way voice-verified

Very few drugs are given to pregnant women anyway. voice-verified

So for example, new medicines that get discovered, they do not give them to pregnant women because of the risk of this. voice-verified

And even though you can test it, there's various models to see if a drug is a teratogen. voice-verified

And they're quite reliable actually as well, by the way. voice-verified

So you could test them and check for teratogenicity. voice-verified

Uh but still very cautious giving drugs to pregnant women 'cause they might affect the developing fetus. voice-verified

But thalidomide was a real disaster, wasn't it? voice-verified

Um, in drug discovery. voice-verified

And we do have huge uh concerns about drug development to make sure it does never happens again, is the overall idea there. voice-verified

But it was a drug that was developed to try and treat morning sickness. voice-verified

They also began to realise, look, uh apartf apart from hyperemesis, the severe end, voice-verified

It's something that's a bit of a nuisance and uncomfortable. voice-verified

And it may be good because it may stop the women ingesting certain things that could be harmful. voice-verified

So it wasn't a disease, if you know what I mean, unless it's the severe end that needed to be treated. voice-verified

So the overall motivation then of Grun and Tail has to be questioned in a sense that they were trying to do something voice-verified

That wasn't maybe needed after all. voice-verified

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