Luke O'Neill

speaker

4,575 appearances 24 recordings 2 series first heard Apr 2026 last heard 3d ago

Luke O'Neill’s voice in public audio — every appearance, attributed to the second.

Trend

recordings per month · last 12 months

Recordings per month over the last 12 months — 24 in all, peaking in Jul 2026 with 6.

Appearances

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Show Me the Science with Luke O'Neill · The Science of Morning Sickness · 27 Aug 2026 podcast

Now you can see now where that's going next. voice-verified

For the poor women who have got severe morning sickness, you might try and limit GDF-15. voice-verified

You wouldn't want to turn it off completely, just ramp it down. voice-verified

It's almost like as if GDF-15 is the um the volume control on nausea and vomiting in the body. voice-verified

Low levels are quite good. voice-verified

They stop you eating and control your metabolism. voice-verified

As as you crank up the volume you begin to feel sick and then you begin to vomit. voice-verified

And hyperemesis, you far too much GDF fifteen. voice-verified

So could a drug be developed then to ramp that down and there's a drug in development already, but things like a caxia that could ramp it down. voice-verified

Now again, very cautious because it's pregnant women, it'll be tested extremely carefully and it'd be you'd wonder actually it'll only be in the hyperemesis, really severe case that you might be able to use it. voice-verified

Yeah. voice-verified

In progress, and we'll see what happens next. voice-verified

But certainly the discovery of GDF-15 in morning severe morning sickness turns out to be really interesting and it may tie into other situations where there's nausea, like chemotherapy, for instance. voice-verified

So that's opened up a whole new avenue of research. voice-verified

And us scientists love this, by the way, because someone discovers something in one lab, my lab reads it, or whoever, oh, I get an idea, I'll work on that a bit here, you know. voice-verified

And that's how science advances. voice-verified

You see, someone makes a fascinating discovery. voice-verified

Getting people thinking and wondering what's gonna happen next to me and Steve or Haddy were now collaborating. voice-verified

He's sending me GDF-15 deficient samples and all kinds of things. voice-verified

So it's a great example of how science can can progress. voice-verified

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