Luke O'Neill
speaker
4,575 appearances
24 recordings
2 series
first heard Apr 2026
last heard 3d ago
Luke O'Neill’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 24 in all, peaking in Jul 2026 with 6.
Appearances
And then as the GDF-15 levels climb, eventually you feel nauseous and then you begin to throw up.
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It's like a dose-dependent thing.
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So it looks like it's GDF-15's tied into control.
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food intake.
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And my lab was working on that aspect.
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And secondly, there's some evidence it can suppress inflammation.
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And we're very interested in that, but that's a separate thing to today's topic.
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But still, I I know all about GDF-15 because of my lab's interest in that protein.
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And Victoria and Honey in my lab, their projects are all about GDF-15 in the context of the immune system.
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Also, what's very interesting is uh nausea during chemo might be GDF-15.
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And Honey's working on cisplatin as an anti-cancer agent.
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So some of the nausea.
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Wouldn't that be useful if the nausea of chemo was caused by GDF-15?
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If you block GDF-15, then you might get rid of nausea, which would be a great benefit for cancer patients.
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And then secondly, very importantly, in cancer you get cachexia.
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That means muscle wasting.
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And again, that seems to be too much GDF-15.
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A big metabolic shift is happening.
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And and there's drugs blocking GDF-15 now to limbic acexia in cancer, and that's a separate thing.
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But for us that here with this topic, GDF-15 is tied into morning sickness and then at the most extreme case hyperamesis.
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Showing 801–820 of 4,575 · page 41 of 229
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