Luke O'Neill
speaker
4,575 appearances
24 recordings
2 series
first heard Apr 2026
last heard 3d ago
Luke O'Neill’s voice in public audio — every appearance, attributed to the second.
Trend
recordings per month · last 12 monthsRecordings per month over the last 12 months — 24 in all, peaking in Jul 2026 with 6.
Appearances
He did a big paper showing it's made by the fetus.
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So isn't that strange?
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So in other words, you're you're pregnant, you're carrying the fetus, the fetus begins to make the GDF-15, it goes into the mother's circulation, goes to the brain, and says, feel a little bit nauseous and maybe throw up or whatever, a little bit.
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So it's almost as if the fetus is sending out a signal to say, Hey mom, don't eat stuff that might harm me.
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Isn't that strange?
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Or get rid of it from your body if you have eaten something that might be harmful.
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So it's a very interesting evolutionary thing there.
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That the fetus goes to the trouble of making this stuff to protect itself.
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Obviously, it's not thinking along those lines, but evolution built that in, isn't it strange?
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They noticed initially the placenta, loads of it in placenta, but then they realized a lot of it's coming from the fetus.
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Now, other bits of the body can make it as well.
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It's not just the fetus, but the fetus is an important source of GDF-15.
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And my lab is now working on GDF-15.
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There's also evidence that GDF-15
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Can block inflammation.
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It's a separate function for GDF-15 outside this.
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And very importantly, as well, it will limit food intake.
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So low levels of GDF-15 are made naturally.
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It's a bit like GLP1, actually.
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And those drugs, like the Ozempic, your body makes it to say eat less.
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Showing 781–800 of 4,575 · page 40 of 229
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