Noemi Fuentes-Polaños

That's the big question.

That's what we are trying to investigate further.

Answer is yes.

In terms of clinical criteria to test every child with a cancer, we strongly believe that's what we should be doing.

However, we still have to follow certain recommendations.

And the recommendations are a step before that testing everyone.

If you have this type of cancer, then you test for this.

If you have that type of cancer, you test for that.

Correct.

Absolutely.

We all have a lot of changes in our genes.

All of us.

And that's what makes us different.

Not all of the changes are pathogenic.

So to confirm that a change that we found on a gene is pathogenic, you need a lot of different experts providing different approach to the same question.

Do we think this change can cause a disease or a risk of cancer?

So it is sometimes tricky to the point that we say, look, this is called unknown significance.

We don't even know the impact of this change yet.

Great question.

The reality is that there is a big proportion of genes that we don't understand what they do.