Norman Swan
speaker
10,274 appearances
109 recordings
1 series
first heard Mar 2020
last heard 11 Aug
Norman Swan’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 2 in all, peaking in Aug 2026 with 1.
Appearances
And just before I get to the Pfizer one, so where we got to with treatment was hydroxychloroquine didn't work.
Ivermectin may work a little bit, but it's really doubtful.
But steroids do work, and that was shown by the British, and reduced mortality by about 20%.
Remdesivir is pretty disappointing in terms of
It probably just reduces hospitalization a little bit, but doesn't do an awful lot of good.
And anti-HIV drugs didn't work and so on.
But this comes to the Pfizer drug is actually not that dissimilar to some anti-HIV drugs because it's called a protease inhibitor.
So what it does is it inhibits replication of the virus, which is what protease inhibitors that are geared towards HIV do as well.
And that's what they're aiming to do, so that it attacks the specific proteases involved.
So a protease is an enzyme that's required
for viruses to replicate themselves.
And the inhibitor inhibits that enzyme and therefore prevents replication.
So that's what they're trying to do.
Very successful in HIV.
We've just got to see whether or not it works with SARS-CoV-2.
They do have side effects, by the way, with HIV.
So this one would have to, you know, the side effect profile would have to be pretty closely monitored.
They can be quite expensive drugs.
So that's the other side of this is what the cost would be.
But this would be treatment for people who have got COVID-19, presumably high risk people.
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