Norman Swann
speaker
14,464 appearances
150 recordings
1 series
first heard Jul 2005
last heard Feb 2013
Norman Swann’s voice in public audio — every appearance, attributed to the second.
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Appearances
Hello and welcome to the Health Report with me, Norman Swann.
Today a mystery a sense of smell with a mind of its own.
Plus sleeping in your genes, the implications of having an Orcadian surname, and many of you do, and a salutary factor or two before you run off to get your genome mapped.
The hunt for genes associated with our health and well being has been on for many years now, and in particular since the human genome was mapped, the genome being the DNA on our chromosomes.
But it's still too expensive and slow to go fishing for genes by sequencing or decoding the DNA of every single one of them, which is why a technique called genome wide association studies have become popular.
They're a much faster way to find neighborhoods or genes on our chromosomes which might be important in the search for causes of common problems and possibly new treatments for them.
For example, research at the University of Oxford in the UK has found a new and surprising gene linked to the risk of stroke.
They've also uncovered some frustrating news about an important vaccine.
Professor Peter Donnelly is director of the Welcome Trust Center for Human Genetics at the University of Oxford, which is a world leader in genome wide association studies.
Before we start that, we're going to talk about your study of a vaccine for pneumococcus, a common cause of pneumonia and meningitis.
There have been a couple of issues about this.
One is that have you knocked off those seven different types and then other dangerous forms of pneumococcus come in and filled the space in the ecosystem, if you like?
And you've been looking at how the bug itself responded to the vaccine.
So you you hope that a vaccine's gonna solve your problem, but it might create another.
Commonly the carotid arteries in the neck get blocked and rubbish flies off and lodges in the brain.
tell me what this five hundred person study you're doing.
Association, you're just taking their whole genome
And how much is it costing per genome to do this?
Aiming for?
Professor Peter Donnelly.
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