Menu
Sign In Search Podcasts Charts People & Topics Add Podcast API Pricing

Paul Turek

👤 Person
716 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

They'll never work naturally. And to get them to work with IVF, you have to single sperm inject them into the egg and then shock the egg with calcium, do a calcium or piezoelectrics to get it to actually fertilize. Because the sperm is important with fertilization, not only has to bind, but the calcium channels are regulated by sperm.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

They'll never work naturally. And to get them to work with IVF, you have to single sperm inject them into the egg and then shock the egg with calcium, do a calcium or piezoelectrics to get it to actually fertilize. Because the sperm is important with fertilization, not only has to bind, but the calcium channels are regulated by sperm.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And what shuts the doors to polyspermia in an egg is calcium activation.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And what shuts the doors to polyspermia in an egg is calcium activation.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So morphology can matter a lot, but it's very rare. So I'd say twice a year in my practice, I'll see this Because everything's failing and everything looks normal. And they ask me what's going on. And I'll look at it really closely and say, you have this issue and there's not much we can do to treat it.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So morphology can matter a lot, but it's very rare. So I'd say twice a year in my practice, I'll see this Because everything's failing and everything looks normal. And they ask me what's going on. And I'll look at it really closely and say, you have this issue and there's not much we can do to treat it.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Now we're going to try sperm sorting technologies, which are out new in the market, microfluidics and things like that. And I've been throwing that at them. Sometimes it works, sometimes it doesn't.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Now we're going to try sperm sorting technologies, which are out new in the market, microfluidics and things like that. And I've been throwing that at them. Sometimes it works, sometimes it doesn't.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

PLZ's data deficiency is one of them recently discovered that runs the calcium channel, which tends to be associated with a certain look like globals of spermia.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

PLZ's data deficiency is one of them recently discovered that runs the calcium channel, which tends to be associated with a certain look like globals of spermia.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

That's one of the 50 we throw off each generation, 50 mutations.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

That's one of the 50 we throw off each generation, 50 mutations.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

I think what I would like to emphasize in this podcast is how fluid evolution actually is. And it's sperm driven and it's transgenerational. So if you ask me, what's the theme for today? I'd say sperm matter a lot, a lot, a lot more than we've given them credit for.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

I think what I would like to emphasize in this podcast is how fluid evolution actually is. And it's sperm driven and it's transgenerational. So if you ask me, what's the theme for today? I'd say sperm matter a lot, a lot, a lot more than we've given them credit for.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So I look at, in my poker analogy of the hand, if everything looks good but the motility is low, I think of short-term toxins. Severity. So things like exposures. So medications. I think about habits, pot, smoking, hot baths. I think about behaviors, lifestyle. So I look for an exposure in that individual. Basically picked up on the history. Varicoceles and exposure, things like that.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

So I look at, in my poker analogy of the hand, if everything looks good but the motility is low, I think of short-term toxins. Severity. So things like exposures. So medications. I think about habits, pot, smoking, hot baths. I think about behaviors, lifestyle. So I look for an exposure in that individual. Basically picked up on the history. Varicoceles and exposure, things like that.

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And if the count's down and the motility's down, I think of a large severe exposure. There's royal flushes and there's four of a kind. My goal when I see that semen analysis and see that patient is to figure out if he's not normal, why?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

And if the count's down and the motility's down, I think of a large severe exposure. There's royal flushes and there's four of a kind. My goal when I see that semen analysis and see that patient is to figure out if he's not normal, why?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Either they give it to me or I get one. I want that there because that's when I look at them, I'd like to have that in front of me to say, what kind of poker hand are you playing?

The Peter Attia Drive
#351 ‒ Male fertility: optimizing reproductive health, diagnosing and treating infertility, and navigating testosterone replacement therapy | Paul Turek, M.D.

Either they give it to me or I get one. I want that there because that's when I look at them, I'd like to have that in front of me to say, what kind of poker hand are you playing?