Professor Luke O'Neill
speaker
1,535 appearances
7 recordings
2 series
first heard Apr 2026
last heard 3 Sep
Professor Luke O'Neill’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 7 in all, peaking in May 2026 with 3.
Appearances
And again, that would have been discovered, oh, 30 odd years ago.
You can take samples of psoriatic skin and study them in the lab.
And I would have worked with labs that do that, you know, and they look at it down the microscope, they analyse it in detail, and they're the ones who began to see loads of T-cells
in the psoriatic lesion, as we call it.
And when I was doing my PhD in London all those years ago, my supervisor said, every time a new immune molecule is found, lo and behold, the psoriasis guys find it in psoriasis.
And it's quite true.
All the immune components are there, but the T cell seems to dominate.
Now, there are different types.
There's plaque psoriasis.
That's the most common one, really, where you get these big patches.
They're called plaques that spread out from the lesion.
That's plaque psoriasis.
Gut eight, that's spots, little pimples, I suppose.
And then you have pustular, and they are big spots full of pus.
Pus is an interesting substance, actually, in itself.
You'll all be familiar with pus that you see in a spot for instance.
What pus is actually is dead neutrophils.
Now neutrophils are a very important cell in the immune system and they fight infection and when they die they form pus.
So whenever you see a bacterial infection you often get pus because the neutrophils have fought the good fight.
They've killed the bacteria and then they form pus.
Showing 1321–1340 of 1,535 · page 67 of 77
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