Shana Kelley

He'll go get exactly the ball that you just threw.

He'll bring it back, but then he won't let it go.

Same thing.

So the sensor catches the protein, but it won't let it go.

It's a very strong complex.

Yeah, so we chose a diabetes model because, you know, diabetes and inflammation go hand in hand, right?

If your glucose is out of range, your inflammation is going to start to spike.

So we thought that would be a good model.

And, you know, we had rats that we allowed to fast and we could see that as they fasted, their pro-inflammatory cytokines would come down.

We had animals that we would inject with insulin and we could see the pro-inflammatory markers come down even faster.

Interestingly, when we injected the rats with insulin to kind of see how that would affect things, we actually saw a little spike in inflammation just from the needle prick.

Like that's how good the resolution is.

So that was very cool to see.

Yeah.

And then we also dose the rats with molecules that would make their inflammation spike, and we could absolutely see that.

So we were able to convince ourselves and the folks that reviewed our paper that we really could watch inflammation in real time in a living animal.

Oh, absolutely.

I mean, the concept is to just, we're going to just go right alongside, you know, the way the CGMs have been developed.

So sensor in the interstitial fluid, app on a phone, being able to track markers that will help us make lifestyle decisions, help us manage disease.

And then there's also a whole set of research applications as well that I think will be really interesting.