Shana Kelley

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179 appearances 1 recordings 1 series first heard Sep 2025 last heard Sep 2025

Shana Kelley’s voice in public audio — every appearance, attributed to the second.

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Ground Truths · Shana Kelley: Biosensors to Track Proteins and Inflammation in Our Blood in Real Time · 14 Sep 2025 podcast

Yeah, absolutely.

You described it very well that for the chronic diseases that are hard to manage, right?

Heart failure is a classic.

You know this better than me that, you know, you have patients in various stages of heart failure and they may be okay and they seem to be, you know, at a steady state.

But then something happens and they wake up and their ankles are swollen and it's not clear what's going on.

Do medications need to be titrated?

You know, if you could see what BNP had been doing over the last 24 to 48 hours, that would probably give you an answer in terms of what action to take next.

So I think chronic disease management is absolutely a place that we can just do so much more for patients if we're able to monitor them properly.

septic patients in the ICU, right?

Really understanding what inflammation, how it's trending there.

And then you mentioned neurodegenerative disease.

I mean, one of the things that I think is really fascinating to think about as an application, maybe not in humans, but in our model organisms, just really understanding neuroinflammation and what happens in the brain, you know, when you have a spike in inflammation, right?

There are people that are diagnosed as being schizophrenic

But they actually just have inflammation in their brains.

And when they're treated appropriately, right, the psychosis goes away.

But we really, it's very much a black box.

So I think we can do a lot for patients if we can take the technology where I would like to.

But we can also answer a lot of questions about how inflammation affects us systemically, but also at the organ level.

Yeah, so that's actually the hard part.

I mean, the inventing and the proof of concept and all, that was hard.

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