Sydney Lupkin
speaker
1,064 appearances
108 recordings
3 series
first heard Dec 2024
last heard 3d ago
Sydney Lupkin’s voice in public audio — every appearance, attributed to the second.
Trend
recordings per month · last 12 monthsRecordings per month over the last 12 months — 93 in all, peaking in Jul 2026 with 21.
Appearances
Amit Sarpatwari is an assistant professor of population medicine at Harvard Medical School, and he says it was an example of the public and private sectors working together at their best to bring forward meaningful medical advancements.
And Emily, none of this would have happened without people knowing about the genetic mutation that causes this cancer in the first place, the Philadelphia chromosome.
That discovery was funded by the National Cancer Institute, which is part of the NIH.
cooperation and taking on risk.
Remember, Brian Drucker moved across the country.
The drug company that would become Novartis took on the financial risk of doing the expensive clinical trials.
The patients took a risk trying a new drug, and then a whole bunch of people moved to heaven and earth to speed up the approval time.
All of this changed medicine.
Though I should add that Gleevec was also considered incredibly expensive when it launched at $26,000 a year.
And that meant even more money back in the early 2000s.
The drug is now generic and much cheaper.
Yep, it's still used.
Brian still prescribes Gleevec and the second, third, and fourth generation drugs that came after.
And he's still able to tell patients that they'll be able to live a normal life.
He told me about one patient who had leukemia as a child and started taking Gleevec.
Eventually, she was able to come off the drug with no recurrence of her cancer, and she now has two kids.
And the researchers kept studying Gleevec, and they found out it actually works for other cancers.
For example, it can also treat a certain kind of gastrointestinal tumor by shutting off its out-of-control growth.
Dr. Drucker, Brian, remembers that he had this one patient who had one of these tumors that he said made his stomach look like he was nine months pregnant.
And he was uncomfortable.
Showing 541–560 of 1,064 · page 28 of 54
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