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Theo Jaffee

πŸ‘€ Speaker
359 total appearances

Appearances Over Time

Podcast Appearances

The a16z Show
The Shift in Global Drug Development

What you've pulled up here, this is, it looks like a table from Wikipedia.

The a16z Show
The Shift in Global Drug Development

Is that right, Krimo?

The a16z Show
The Shift in Global Drug Development

Yeah, yeah.

The a16z Show
The Shift in Global Drug Development

It's a bunch of different compounds that all have the same or a similar target.

The a16z Show
The Shift in Global Drug Development

You said this is a cancer-

The a16z Show
The Shift in Global Drug Development

Yeah.

The a16z Show
The Shift in Global Drug Development

It's a cancer drug.

The a16z Show
The Shift in Global Drug Development

And so this target here, this is the – what is that?

The a16z Show
The Shift in Global Drug Development

Do you know what that is?

The a16z Show
The Shift in Global Drug Development

The PD-1?

The a16z Show
The Shift in Global Drug Development

Is that like a – Yeah.

The a16z Show
The Shift in Global Drug Development

Maybe you're getting here, Craig, but like, what is the, what is the kind of underlying institutional or process thing that's driving this?

The a16z Show
The Shift in Global Drug Development

I'll get to that.

The a16z Show
The Shift in Global Drug Development

I can see there'd be ethical concerns.

The a16z Show
The Shift in Global Drug Development

You know, there'd be ethical concerns.

The a16z Show
The Shift in Global Drug Development

You can see... Yeah, people might get too healthy.

The a16z Show
The Shift in Global Drug Development

Yeah, you wouldn't want to get too healthy.

The a16z Show
The Shift in Global Drug Development

And maybe just to explain that for one second, stupid naive question, but it seems like that's just a kind of function of if you have a small effect size for a given intervention, you need a much larger population before that becomes statistically significant, right?

The a16z Show
The Shift in Global Drug Development

That's right.

The a16z Show
The Shift in Global Drug Development

Yeah, exactly.