The a16z Show

How to Build with the Department of Defense

02 Apr 2025

Contributed by Lukas

When people think about startups working with the government, the phrase “black box” often comes up. But what if that box is finally being pried o...

The Top 100 GenAI Products, Ranked and Explained

26 Mar 2025

Contributed by Lukas

This month, a16z’s Consumer team released the fourth edition of the GenAI 100 — a data-driven ranking of the top 50 AI-first web products and mobi...

Jensen Huang and Arthur Mensch on Winning the Global AI Race

21 Mar 2025

Contributed by Lukas

The global race for AI leadership is no longer just about companies—it’s about nations. AI isn’t just computing infrastructure; it’s cultural ...

Why AI Voice Feels More Human Than Ever

18 Mar 2025

Contributed by Lukas

AI voice technology has been around for years — think Siri or Alexa — but the magic has been missing. That’s changing, and quickly!In this episo...

From Thesis to Meme to Fund: Building American Dynamism

11 Mar 2025

Contributed by Lukas

For over a century, the United States has been the birthplace of world-changing innovation – from the Wright brothers’ first flight to the inventi...

What Founders Get Wrong About Scaling – With Carta’s CEO

07 Mar 2025

Contributed by Lukas

Henry Ward, cofounder and CEO of Carta, has spent over a decade scaling his company from an early-stage startup to a 2,000-person industry leader. In ...

Creativity vs Control: Where AI Fits in the Creative Toolbox

25 Feb 2025

Contributed by Lukas

Being a creator in 2025 is tough—but building for creators is even harder. Perhaps no one understands this conundrum better than Scott Belsky. As th...

Who Will Own the Internet? a16z’s Chris Dixon on AI and Crypto

20 Feb 2025

Contributed by Lukas

Technology doesn’t grow in isolation—it evolves in waves. Just as mobile, cloud, and SaaS shaped the internet of the past 20 years, so too could c...

The Critical Technology in Finding Critical Materials

11 Feb 2025

Contributed by Lukas

Critical materials like copper, lithium, and gallium have been mined for decades, but their role in core technologies, geopolitics, and the energy tra...

DeepSeek: America’s Sputnik Moment for AI?

06 Feb 2025

Contributed by Lukas

Two words have caught the Internet by storm. DeepSeek. The Chinese reasoning model r1 is rivaling others at the frontier with an open-source MIT lice...

Ben Horowitz Sharing History with Dr. Clarence Jones, MLK's Speechwriter

01 Feb 2025

Contributed by Lukas

This week, a16z cofounder Ben Horowitz had a rare and invaluable conversation with Dr. Clarence B. Jones, a pivotal figure in American history. Dr. J...

How AI Is Changing Warfare with Brian Schimpf, CEO of Anduril

28 Jan 2025

Contributed by Lukas

How is AI reshaping modern warfare? Speaking with a16z Growth General Partner David George, Anduril cofounder and CEO Brian Schimpf discusses how AI ...

RIP to RPA: How AI Makes Operations Work

22 Jan 2025

Contributed by Lukas

Intelligent automation is transforming industries by tackling messy, unstructured workflows that traditional Robotic Process Automation (RPA) couldn’...

Marc Andreessen: Can Tech Finally Fix Healthcare?

15 Jan 2025

Contributed by Lukas

Healthcare is a $4 trillion industry, making up nearly a fifth of the U.S. economy—but despite having some of the best doctors and advanced technolo...

Building Substack: Reinventing Culture through Subscriptions

09 Jan 2025

Contributed by Lukas

In this episode, Substack cofounder and CEO Chris Best joins a16z General Partner Andrew Chen to discuss the origins and evolution of Substack, a plat...

Crypto Trends for 2025: Stablecoins, App Stores, UX, and More

03 Jan 2025

Contributed by Lukas

with @sambroner @meigga @darenmatsuoka @jneu_net @chrislyons and @rhhackett @smc90Welcome to our special end-of-year episodes -- which also look ahead...

Super Staffing Healthcare, Codifying Compliance, & Scaling Services

30 Dec 2024

Contributed by Lukas

As we prepare to step into 2025, the possibilities for applied AI are reshaping industries in profound ways. In this episode, a16z General Partners J...

The Race for AI—Search, National Infrastructure, & On-Device AI

25 Dec 2024

Contributed by Lukas

The AI race is on, and 2025 could be its most transformative year yet.In this episode, a16z General Partners Anjney Midha and Jennifer Li, and Partner...

Jobs of the Future, Harnessing Earth Observation, & Gaming Tech Advances

20 Dec 2024

Contributed by Lukas

As 2025 begins, industries are evolving at unprecedented speed: robots are revolutionizing manufacturing, terabytes of earth observation data are driv...

Scaling Shopify: Tobias Lütke and Ben Horowitz on Building a Global Giant

16 Dec 2024

Contributed by Lukas

In this episode of Web3 with a16z, Shopify CEO and cofounder Tobias Lütke joins a16z cofounder Ben Horowitz for a conversation recorded live at the a...

How AI is Transforming Labor Markets

11 Dec 2024

Contributed by Lukas

Did you know the U.S. nurse labor market is over $600 billion annually, but the dedicated software market for nurses is almost zero?In this episode Ge...

Fixing Education in America: What's Stopping Us?

06 Dec 2024

Contributed by Lukas

Over half of Americans live in childcare deserts, while 90% of brain development happens before the age of five. All the while, education and childcar...

Prediction Markets and Beyond

02 Dec 2024

Contributed by Lukas

This episode was originally published on our sister podcast, web3 with a16z. If you’re excited about the next generation of the internet, check out ...

Death of a Salesforce: Why AI Will Transform Sales

25 Nov 2024

Contributed by Lukas

Sales is evolving. AI-native systems are replacing traditional CRM tools, capturing unstructured insights from emails, Slack, surveys, and more in rea...

The Longevity Imperative: Redefining the Way We Age

18 Nov 2024

Contributed by Lukas

What if the biggest challenge of our time isn’t living longer, but living better? In this episode, we’re tackling one of humanity’s greatest ac...

Rebuilding America's Industrial Backbone

11 Nov 2024

Contributed by Lukas

America is a country of immense wealth, but our manufacturing infrastructure is struggling to keep pace.In this episode, we discuss the overlooked cri...

Autonomy Across Air, Land, and Sea

04 Nov 2024

Contributed by Lukas

2024 has been a milestone year for autonomous tech. Waymo’s fully autonomous driver has surpassed 20 million miles, while FAA approvals now allow c...

State of Crypto 2024: Builder Energy, U.S. Election, Stablecoins, AI, More

29 Oct 2024

Contributed by Lukas

We take you behind the scenes of our newly released, annual State of Crypto Report — a16z crypto's analysis of the latest data and trends that have ...

Tesla's Road Ahead: The Bitter Lesson in Robotics

24 Oct 2024

Contributed by Lukas

What does Rich Sutton’s "Bitter Lesson" reveal about the decisions Tesla is making in its pursuit of autonomy?In this episode, we dive into Tesla’...

The Story of Apple Pay with Jennifer Bailey

22 Oct 2024

Contributed by Lukas

In 2024, marking 10 years since its launch, Apple Pay now boasts hundreds of millions of consumers in 78 markets, at checkout on millions of websites ...

Building a Thriving AI Ecosystem with Lisa Su

17 Oct 2024

Contributed by Lukas

Lisa Su has transformed AMD into a global leader in AI and high-performance computing.In this episode of the AI Revolution (AIR) series , Bob Swan, a1...

The Deepfake Dilemma: The Technology, Policy, and Economy

11 Oct 2024

Contributed by Lukas

Deepfakes—AI-generated fake videos and voices—have become a widespread concern across politics, social media, and more. As they become easier to c...

A Big Week in Tech: NotebookLM, OpenAI’s Speech API, & Custom Audio

08 Oct 2024

Contributed by Lukas

Last week was another big week in technology. Google’s NotebookLM introduced its Audio Overview feature, enabling users to create customizable podc...

From Swipe to Scale: How Tinder Became #1

03 Oct 2024

Contributed by Lukas

In 1995, just 2% of couples met online. Today, that number has surged to over 50%, making online dating the top way couples connect.In this episode, a...

Human Data is Key to AI: Alex Wang from Scale AI

24 Sep 2024

Contributed by Lukas

What if the key to unlocking AI's full potential lies not just in algorithms or compute, but in data? In this episode, a16z General Partner David Geo...

The Frontier of Spatial Intelligence with Fei-Fei Li

19 Sep 2024

Contributed by Lukas

Fei-Fei Li and Justin Johnson are pioneers in AI. While the world has only recently witnessed a surge in consumer AI, our guests have long been laying...

Apple’s Big Reveals, OpenAI’s Multi-Step Models, and Firefly Does Video

14 Sep 2024

Contributed by Lukas

This week in consumer tech: Apple’s big reveals, OpenAI’s multi-step reasoning, and Adobe Firefly’s video model.Olivia Moore and Justine Moore, ...

Grand Challenges in Healthcare AI

07 Sep 2024

Contributed by Lukas

Vijay Pande, founding general partner, and Julie Yoo, general partner at a16z Bio + Health, come together to discuss the grand challenges facing healt...

Governing democracy, the internet, and boardrooms

02 Sep 2024

Contributed by Lukas

with @NoahRFeldman, @ahall_research, @rhhackettWelcome to web3 with a16z. I'm Robert Hackett and today we have a special episode about governance in m...

It’s Time to Build in Healthcare

28 Aug 2024

Contributed by Lukas

Half of prescribed medications are never taken, and 88% of Americans are metabolically unhealthy. Despite spending 20% of our GDP on healthcare—twic...

Latin America: A Tech Powerhouse?

24 Aug 2024

Contributed by Lukas

Latin America is emerging as a tech powerhouse, but it's not a one-size-fits-all market. In this episode, we explore why what works in Argentina won’...

The SSN Breach: What Now?

18 Aug 2024

Contributed by Lukas

In this episode, we cover the recent data breach of nearly 3B records, including a significant number of social security numbers. Joining us to discus...

Building Innovation Hubs: The UK & Beyond

14 Aug 2024

Contributed by Lukas

This episode from Web3 with a16z Crypto, is all about innovation on a global scale, exploring both ecosystem and individual talent levels. We examine ...

The Olympics of Talent: France's Tech Boom

09 Aug 2024

Contributed by Lukas

Once criticized for lacking ambition, French founders are now aiming to create the world’s largest companies. With a thriving ecosystem attracting t...

Building the World's Most Trusted Driver

05 Aug 2024

Contributed by Lukas

Waymo's autonomous vehicles have driven over 20 million miles on public roads and billions more in simulation.In this episode, a16z General Partner Da...

From AI to Instant Replay: The Technology Behind the Olympics

03 Aug 2024

Contributed by Lukas

The Olympics features over 11,000 athletes competing in 32 sports, attracting an audience of more than 10 million.In this episode, Charlie Ebersol, co...

When AI Meets Art

30 Jul 2024

Contributed by Lukas

On June 27th, the a16z team headed to New York City for the first-ever AI Artist Retreat at their office. This event brought together the builders beh...

Founders Playbook: Lessons from Riot, Discord, & More

25 Jul 2024

Contributed by Lukas

Gaming is not just entertainment—it's a revolution reshaping our culture, technology, and economy. a16z’s Jonathan Lai and Andrew Chen dive into ...

Transitioning From Gymnast to Investor with Aly Raisman

17 Jul 2024

Contributed by Lukas

Former gymnast and current investor Aly Raisman joins general partner Julie Yoo and investment partner Daisy Wolf of a16z Bio + Health.In this episode...

Live at Tech Week: Delivering AI Products to Millions

12 Jul 2024

Contributed by Lukas

Less than two years since the breakthrough of text-based AI, we now see incredible developments in multimodal AI models and their impact on millions o...

Marc Andreessen on Building Netscape & the Birth of the Browser

08 Jul 2024

Contributed by Lukas

"The Ben & Marc Show," featuring a16z co-founders Marc Andreessen and Ben Horowitz. In this special episode, Marc and Ben dive deep into the REAL sto...

The Art of Technology, The Technology of Art

03 Jul 2024

Contributed by Lukas

We know that technology has changed art, and that artists have evolved with every new technology — it’s a tale as old as humanity, moving from cav...

Cybersecurity's Past, Present, and AI-Driven Future

26 Jun 2024

Contributed by Lukas

Is it time to hand over cybersecurity to machines amidst the exponential rise in cyber threats and breaches?We trace the evolution of cybersecurity fr...

The Science and Supply of GLP-1s

19 Jun 2024

Contributed by Lukas

Brooke Boyarsky Pratt, founder and CEO of knownwell, joins Vineeta Agarwala, general partner at a16z Bio + Health.Together, they talk about the value ...

The State of AI with Marc & Ben

14 Jun 2024

Contributed by Lukas

In this latest episode on the State of AI, Ben and Marc discuss how small AI startups can compete with Big Tech’s massive compute and data scale adv...

Predicting Revenue in Usage-based Pricing

10 Jun 2024

Contributed by Lukas

Over the past decade, usage-based pricing has soared in popularity. Why? Because it aligns cost with value, letting customers pay only for what they u...

California's Senate Bill 1047: What You Need to Know

06 Jun 2024

Contributed by Lukas

On May 21, the California Senate passed bill 1047.This bill – which sets out to regulate AI at the model level – wasn’t garnering much attention...

The GenAI 100: The Apps that Stick

27 May 2024

Contributed by Lukas

Consumer AI is moving fast, so who's leading the charge? a16z Consumer Partners Olivia Moore and Bryan Kim discuss our GenAI 100 list and what it tak...

Finding a Single Source of AI Truth With Marty Chavez From Sixth Street

22 May 2024

Contributed by Lukas

a16z General Partner David Haber talks with Marty Chavez, vice chairman and partner at Sixth Street Partners, about the foundational role he’s had i...

A Big Week in AI: GPT-4o & Gemini Find Their Voice

19 May 2024

Contributed by Lukas

This was a big week in the world of AI, with both OpenAI and Google dropping significant updates. So big that we decided to break things down in a new...

Remaking the UI for AI

16 May 2024

Contributed by Lukas

Make sure to check out our new AI + a16z feed: https://link.chtbl.com/aiplusa16z a16z General Partner Anjney Midha joins the podcast to discuss what'...

How Discord Became a Developer Platform

10 May 2024

Contributed by Lukas

In 2009 Discord cofounder and CEO, Jason Citron, started building tools and infrastructure for games. Fast forward to today and the platform has over ...

Securing the Black Box: OpenAI, Anthropic, and GDM Discuss

06 May 2024

Contributed by Lukas

Human nature fears the unknown, and with the rapid progress of AI, concerns naturally arise. Uncanny robocalls, data breaches, and misinformation floo...

Can AI Advance Science? DeepMind's VP of Science Weighs In

01 May 2024

Contributed by Lukas

In recent years, the AI landscape has seen huge advancements, from the release of Dall-E 2 in April 2022 to the emergence of AI music and video models...

Next-Gen Gaming: AI Souls, Real-time Culture, Personalized Avatars

26 Apr 2024

Contributed by Lukas

Over 3,700 companies applied to a16z’s SPEEDRUN. In this episode, we meet the founders pushing the boundaries of what games can be.From the fusion o...

Why America Must Lead in AI Investment with Senator Young (R-IN)

22 Apr 2024

Contributed by Lukas

Senator Todd Young (R-IN) speaks with a16z General Partner Martin Casado about the importance of open innovation and American leadership in AI, and wh...

Game On: Marc Andreessen & Andrew Chen Talk Creative Computers

17 Apr 2024

Contributed by Lukas

The gaming industry stands as a pioneer of cutting-edge technologies, ushering in innovations like GPUs, virtual and augmented reality, physics engine...

Inside the Department of Defense and its Vision for the Future

10 Apr 2024

Contributed by Lukas

From air-defining radar and electronic systems that helped the Allies win World War II, the origins of Silicon Valley are deeply rooted in government ...

Politics & the Future of Tech with Marc Andreessen and Ben Horowitz

05 Apr 2024

Contributed by Lukas

“If America is going to be America in the next one hundred years, we have to get this right.” - Ben HorowitzThis week on “The Ben & Marc Show”...

The Real Price of Healthcare with Mark Cuban

29 Mar 2024

Contributed by Lukas

From judging inventions on “Shark Tank” to reshaping the image of NBA ownership, Mark Cuban is known for many things. In this chat with a16z Gener...

Devoting Your Life to Reinventing a Broken System

25 Mar 2024

Contributed by Lukas

At the a16z LP Summit, we brought hundreds of our limited partners and portfolio founders together in Las Vegas.The event was truly overflowing with s...

Bringing AI to the Masses with Adam D’Angelo

20 Mar 2024

Contributed by Lukas

Generative AI has initiated a transformative shift, reshaping our world in unprecedented ways. In a16z's AI Revolution series, we engage some of the m...

A Nuclear Comeback: Are New Reactors the Answer?

15 Mar 2024

Contributed by Lukas

Nuclear energy accounts for 20% of the electricity in the United States, but remarkably, 2023 marked the commissioning of the U.S.'s first new nuclear...

Intelligence in the Age of AI with new CTO of the CIA

11 Mar 2024

Contributed by Lukas

Artificial intelligence has taken the world by storm. But despite the hype around personalized avatars or podcast language translation, artificial int...

From Silicon Valley to the Pentagon: The Future of Defense Innovation

07 Mar 2024

Contributed by Lukas

The last few decades have been a period of transition for defense. An increasing number of startups have begun to rival large defense primes, the indu...

What is American Dynamism?

04 Mar 2024

Contributed by Lukas

American Dynamism. A term coined by a16z General Partner, Katherine Boyle, two years ago, when she and David Ulevitch founded the firm's American Dyna...

The Quest for True Signal: How Zynga Spotted Mobile

27 Feb 2024

Contributed by Lukas

You might recognize the name Mark Pincus but we almost guarantee you recognize the game Farmville. Mark Pincus is the founder and longtime CEO of Zyn...

Beyond Uncanny Valley: Breaking Down Sora

24 Feb 2024

Contributed by Lukas

In early 2024, the notion of high fidelity, believable AI-generated video seemed a distant future to many. Yet, a mere few weeks into the year, OpenAI...

Fraying Wires: The Decentralization of the Electric Grid

15 Feb 2024

Contributed by Lukas

The electric grid needs an update. In this explainer, a16z Partner Ryan McEntush discusses the escalating complexity of the grid, unveils its vulnera...

Fixing Higher Education & New Startup Opportunities with Marc and Ben

08 Feb 2024

Contributed by Lukas

"The Ben & Marc Show" features a16z's co-founders Ben Horowitz & Marc Andreessen. In this episode, Marc and Ben continue their in-depth exploration of...

Read Write Own: A New Era

02 Feb 2024

Contributed by Lukas

with @cdixon @rhhackettWelcome to the web3 with a16z crypto podcast. I'm Robert Hackett, an editor here at a16z crypto, and I'm here with Chris Dixon,...

The What, Who, and When with IPOs

29 Jan 2024

Contributed by Lukas

In 2022 and 2023, US IPOs hit decade lows after the record high of 2021. Now, in 2024, will the IPO window reopen?In this episode, we revisit a conver...

Jobs of the Future

24 Jan 2024

Contributed by Lukas

(00:00) - The Future of Jobs(03:15) - Job growth over the last 80 years(05:06) - The shelf-life of jobs(09:11) - Education trends(12:25) - The importa...

Introducing Raising Health: Fireside Chat with Sean Duffy

18 Jan 2024

Contributed by Lukas

Big news from a16z: Bio Eats World, our sibling show from a16z Bio+Health, is now Raising Health!We’re excited to share Raising Health’s first epi...

Crisis in Higher Ed & Why Universities Still Matter with Marc & Ben

14 Jan 2024

Contributed by Lukas

In this one-on-one conversation, Marc and Ben tackle the university system – what has certainly been a hot topic that’s been dominating the news o...

Drones, Data, and Deterrence: Technology's Role in Public Safety

10 Jan 2024

Contributed by Lukas

Flock is a public safety technology platform that operates in over 4,000 cities across the United States, and solves about 2,200 crimes daily. That’...

DNA's Potential to Store the World's Data

05 Jan 2024

Contributed by Lukas

Nature’s blueprint – DNA – is an incredibly efficient machine. You cannot see it with the naked eye, yet it can last for hundreds, maybe even mi...

A Year of Unlocks: 2023 In AI, Healthcare, Housing, and More

31 Dec 2023

Contributed by Lukas

As we close off 2023, we wanted to revisit some of our favorite episodes from the last year. From AI hardware, to healthcare regulation, to disrupting...

The Future of Longevity with Tony Robbins

26 Dec 2023

Contributed by Lukas

Welcome to “The Ben & Marc Show”, featuring a16z’s co-founders Ben Horowitz and Marc Andreessen.  In this week’s episode, Marc and Ben are jo...

2024 Big Ideas: Developer Influence, Maritime Upgrades, and New Video Intelligence

22 Dec 2023

Contributed by Lukas

A new age of maritime exploration, the rise of the developer as a buyer in financial services, and more applications for computer vision and video int...

Text to Video: The Next Leap in AI Generation

20 Dec 2023

Contributed by Lukas

General Partner Anjney Midha explores the cutting-edge world of text-to-video AI with AI researchers Andreas Blattmann and Robin Rombach. Released in...

2024 Big Ideas: Voice-First Apps, AI Moats, Never-Ending Games, and Anime Takes Off

15 Dec 2023

Contributed by Lukas

Voice-First Apps, AI Moats, Never-Ending Games, and Anime. We asked over 40 partners across a16z to preview one big idea they believe will drive innov...

Safety in Numbers: Keeping AI Open

11 Dec 2023

Contributed by Lukas

Arthur Mensch is the co-founder of Mistral and the co-author of Deepmind’s pivotal 2022 "Chinchilla" paper.In September 2023, Mistral released Mistr...

2024 Big Ideas: Miracle Drugs, Programmable Medicine, and AI Interpretability

08 Dec 2023

Contributed by Lukas

Smart energy grids. Voice-first companion apps. Programmable medicines. AI tools for kids.
We asked over 40 partners across a16z to preview one big ...

The Quest for AGI: Q*, Self-Play, and Synthetic Data

04 Dec 2023

Contributed by Lukas

One topic at the center of the AI universe this week is a potential breakthrough called Q*. Little has been revealed about this OpenAI project, other ...

Financial Freedom, Company Building, More with David Marcus

28 Nov 2023

Contributed by Lukas

with @davidmarcus @smc90This wide-ranging conversation covers company building, big to small -- including what cadence and when is the right "time" to...

When Business is Battle: Inside the Boardrooms of the CEOs that Survived the Storm

23 Nov 2023

Contributed by Lukas

Taking a company from idea to household name is always difficult. But the past few years presented challenges that caught even the most-seasoned CEOs ...

The Worlds She Sees with Godmother of AI, Fei-Fei Li

13 Nov 2023

Contributed by Lukas

Fei-Fei Li, PhD,  Professor in the Computer Science Department at Stanford University, and Co-Director of Stanford’s Human-Centered AI Institute, j...

From Sims to Sapiens: Crafting Reality with Code

06 Nov 2023

Contributed by Lukas

Is it possible to construct a virtual society that authentically replicates human behavior? AI Town, a virtual town experiment where AI residents live...

Fintech Fuels Global Payments

30 Oct 2023

Contributed by Lukas

Software crosses borders effortlessly. The globalization of money, however, is considerably more challenging. This is especially true for multinationa...