Alzheimer’s Breakthrough with Dr. Josh Helman, MD
How Spike Protein May Accelerate Alzheimer’s & Cognitive Decline | Dr. Mobeen Syed
28 Aug 2025
Could spike protein be the hidden culprit behind brain fog, cognitive decline, and even Alzheimer's disease? Dr. Mobeen Syed (also called Dr. Mobeen or DrBeen) joins me to discuss the concerning persistence of the spike protein in the body and its potential to accelerate the progression of neurodegenerative conditions.In this thought-provoking conversation, you'll learn about the latest studies revealing the impact of the spike protein on brain health and Alzheimer's disease. Dr. Mobeen discusses how it lingers in the body long after infection or vaccination, potentially causing long-term damage. We’ll explore the mechanisms by which the spike protein enters the brain, disrupts the blood-brain barrier, and leads to inflammation and cognitive decline.If you’re concerned about Alzheimer's or want to understand how to protect your brain, don't miss this episode. Get informed, and join us in the fight against cognitive decline.This episode is sponsored by Organifi- Get 20% off organic superfood blends at www.organifi.com/DRJOSH with code DRJOSH“Controlling inflammation does not fix the problem, but it fixes or reduces the damage done because of the problem.” ~ Dr. Mobeen Syed, MD, MScIn this Episode03:21 - Can spike protein persist in the brain for months or even years?22:51 - How the spike protein damages the brain46:45 - Spike protein and its role in endothelial cell dysfunction53:36 - Vaccine-derived vs. infection-derived spike protein1:06:49 - Managing spike protein damage: Is recovery possible?1:19:19 - Interventional studies on TLR antagonistsLinks to the Articles: -Spike Protein Fragments Promote Alzheimer’s Amyloidogenesis | ACS Applied Materials & Interfaces - https://pubs.acs.org/doi/10.1021/acsami.3c09815-SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein | Molecular Psychiatry - https://www.nature.com/articles/s41380-022-01831-0?utm_source=chatgpt.com-Immunological and Antigenic Signatures Associated with Chronic Illnesses after COVID-19 Vaccination | medRxiv - https://www.medrxiv.org/content/10.1101/2025.02.18.25322379v2-Immunological and Antigenic Signatures Associated with Chronic Illnesses after COVID-19 Vaccination - https://www.medrxiv.org/content/10.1101/2025.02.18.25322379v2.full.pdf-Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19: Cell Host & Microbe - https://www.cell.com/cell-host-microbe/fulltext/S1931-3128%2824%2900438-4?utm_source=chatgpt.com-Unraveling the SARS-CoV-2 spike protein long-term effect on...
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