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Biohacking with Brittany

The Natural "Ozempic"? How a Bitter Hop Compound Crushes Cravings with Sarah Kennedy, CEO of Calocurb

19 Aug 2025

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Sarah Kennedy, CEO of Calocurb, joins me to explore the science of appetite regulation, hormone health, and why bitter plant compounds may be the key to modern weight challenges. We unpack the fascinating 15-year research journey that began with a $30M government grant in New Zealand and led to the discovery of a specific hop variety that increases satiety hormones by 600%. Sarah contrasts Calocurb with drugs like Ozempic, sharing why a natural, hormone-supportive approach could be the future of weight management. From PMS cravings to perimenopause, from post-Ozempic rebound hunger to late-night snacking, Sarah explains how Calocurb works with your body rather than against it. WE TALK ABOUT:  14:00 – The surprising science of bitter taste receptors in your gut 19:00 – How Calocurb compares to Ozempic and Wegovy 26:25 – Hormonal influences on hunger (menstrual cycle, perimenopause, menopause) 28:30 – Why 70% of people are overweight in today's food environment 34:50 – Safety guidelines for women, pregnancy, and breastfeeding 39:00 – How to time Calocurb for cravings, late-night snacking, and travel 44:30 – Why women in their luteal phase may benefit most 47:30 – Addressing childhood obesity and adolescent use of Calocurb SPONSORS: Join me in Costa Rica for Optimize Her, a 5-night luxury women's retreat in Costa Rica with yoga, healing rituals, and biohacking workshops—only 12 spots available. Spark effortless cellular renewal and longevity with SpermidineLIFE (code: BIOHACKINGBRITTANY) —the clinically studied, easy-to-take caps that nudge your body's autophagy switch every day. RESOURCES: Trying to conceive? Join my Baby Steps Course to optimize your fertility with biohacking. Free gift: Download my hormone-balancing, fertility-boosting chocolate recipe. Explore my luxury retreats and wellness events for women. Shop my faves: Check out my Amazon storefront for wellness essentials. Calocurb website (get 10% OFF using my link) and Instagram LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music

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