The Red Invader: Serratia marcescens and Diabetic Foot Ulcers

In this episode of Diabetic Foot Files we explore Serratia marcescens — a red-pigment producing, opportunistic gram-negative bacterium that can rapidly worsen diabetic foot ulcers. We cover its history, microbiology and virulence, clinical clues (including the telltale pink drainage on dressings), diagnostic tips, and culture-directed treatment strategies. The episode also reviews wound care approaches to disrupt biofilm, antibiotic options guided by sensitivities, prevention steps for clinics and patients, and real-world case examples to help clinicians protect limbs and improve outcomes.

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