Extend Podcast with Darshan Shah, MD
64. LP(a): The Massively Important, But Totally Overlooked Biomarker of Heart Attacks, Strokes, and Heart Disease
22 May 2025
In this episode of Extend, we're digging into one of the most dangerous—and most overlooked—drivers of heart disease: LP(a). You could have a clean lifestyle, normal labs, and still be at high risk for a heart attack or stroke. Why? Because LP(a) isn't included in standard cholesterol tests—and 1 in 5 people have elevated levels without knowing it. I break down what LP(a) actually is, why it's more inflammatory and damaging than LDL, and how it contributes to plaque, heart attacks, strokes, and valve disease. You'll learn why lifestyle changes don't lower it, what to do if your levels are high, and how cutting-edge RNA therapies could offer hope. I also share exactly which labs and scans to request so you're not flying blind. ➡️ If you care about preventing cardiovascular disease, this is essential listening. It's time to add LP(a) to the conversation. I Also Discuss: The stealth cholesterol marker no one's testing for Think your cholesterol panel is fine? Here's what it's missing LP(a): the hidden culprit behind "healthy" heart attacks This could be why young people are having strokes The one stat that should have everyone talking Got high LP(a)? Here's your action plan The game-changing drugs that silence LP(a) at the source Thank You for Our Sponsors: Deliverance: Give your liver the care it deserves! Deliverance is a powerful plant-based formula designed to support and restore liver health. Get 10% off your first order with code DRSHAH at loveyourliver.com Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/
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