In this episode of KDIGO Conversations in Nephrology, Dr. Kirk Campbell speaks with Dr. Laura Mariani about the central role of proteinuria reduction in the management of focal segmental glomerulosclerosis (FSGS). The discussion explores the biologic link between podocyte injury and proteinuria, the goals and findings of the PARASOL initiative, and how proteinuria may help guide clinical trial design and treatment decisions in FSGS. Dr. Mariani also reflects on the importance of collaboration and data sharing in advancing therapies for rare glomerular diseases. This episode is part of a special three-part KDIGO Conversations in Nephrology series exploring advances in podocyte biology, disease mechanisms, emerging therapies, and the evolving clinical management of FSGS.

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“What did the council decide on item 42?” — answered with the speaker and the moment.

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