NEJM This Week — December 11, 2025

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Recorded10 Dec 2025

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Handlerec:14495737

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This week, we look at new studies on high-dose influenza vaccines for older adults, antiplatelet therapy after coronary surgery, and HER2-targeted immunotherapy for advanced bladder cancer. We review complex regional pain syndrome and a pediatric case of fever and rash. We also explore FDA innovation and safety, aspirin’s role in metastasis prevention, the meaning of “the good doctor,” smallpox in the Revolution, and how AI may reshape medical science.

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“What did the council decide on item 42?” — answered with the speaker and the moment.

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