The 2026 Fierce 50 brings together scientists, physicians, public health leaders, patient advocates and organizations working in very different ways to move healthcare and the life sciences forward. This year’s honorees are developing new medicines, closing gaps in access and representation, tackling health literacy and misinformation, rethinking disease prevention and finding new ways to bring public health information into the communities that need it. In this episode of "Podnosis," Fierce Healthcare and Life Sciences Editor-in-Chief Ayla Ellison looks at some of the stories that stood out from this year’s honorees, from Revolution Medicines’ bet on the once “undruggable” RAS cancer target and the protein-design work of David Baker, Ph.D., to Michael Osterholm, Ph.D., and his decision to delay stepping back from public health. The episode also explores how honorees including Lisa Fitzpatrick, M.D., Hip Hop Public Health, Eric Topol, M.D., and Mary Owen, M.D., are rethinking trust, communication, prevention and health equity. To learn more about the topics in this episode: Fierce 50 of 2026 See omnystudio.com/listener for privacy information.

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