The Sepsis Spectrum
Episodes
When Sepsis Hits the Lungs
23 Dec 2025
Contributed by Lukas
Sepsis doesn’t just overwhelm the body, it can turn the lungs into ground zero for multi-organ dysfunction. In this episode, host Nicole Kupchik sit...
What happens to the kidneys during sepsis?
16 Dec 2025
Contributed by Lukas
Acute kidney injury (AKI) is far more dangerous and complex than previously understood. In this episode, host Nicole Kupchik sits down with Dr. Gonzal...
Is the gut the real engine of sepsis?
09 Dec 2025
Contributed by Lukas
Host Nicole Kupchik is joined by Dr. Kaveh Hoda to unpack one of the most overlooked drivers of sepsis: the gut. Often called “the motor of MODS,”...
Can sepsis turn the liver against you?
02 Dec 2025
Contributed by Lukas
In this episode, Nicole Kupchik sits down with Dr. Craig Jenne to unravel how the liver’s immune response shifts during sepsis. Together, they explo...
The Nerve That Could Stop Sepsis
25 Nov 2025
Contributed by Lukas
What if the key to controlling inflammation, and even saving lives from sepsis, lies not in the bloodstream, but in the brain? In this episode, Nicole...
Can sepsis break your heart?
18 Nov 2025
Contributed by Lukas
When sepsis strikes, the damage doesn’t always end with the infection. Nicole Kupchik is joined by Dr. Mitchell Elkind from the American Heart Assoc...
What's next in sepsis? | Season 2 Coming Soon!
29 Sep 2025
Contributed by Lukas
Season 2 is just around the corner for The Sepsis Spectrum! In this special bonus episode, Nicole Kupchik reflects on what we learned last season, how...
Are we failing sepsis survivors who need us most?
19 Aug 2025
Contributed by Lukas
What you don’t track, you can’t fix, and too often, we’re not even looking. Nicole is joined by sepsis survivors Dr. Hilary Spangler and Jackie ...
Can we humanize post-sepsis care?
12 Aug 2025
Contributed by Lukas
When crisis hits every layer of care, how do you keep patients feeling human? Nicole is joined by Dr. Mark Mikkelsen and sepsis survivor Katy Grainger...
Can patient harm drive better sepsis prevention?
05 Aug 2025
Contributed by Lukas
Sometimes what we call prevention is really just harm repackaged. Nicole, Dr. Hudson Garrett, and Armando Nahum dig into the paradoxes of infection co...
Are sepsis protocols ready for AI?
29 Jul 2025
Contributed by Lukas
How can we diagnose what we haven’t yet defined? Nicole welcomes Dr. Shamim Nemati and Dr. Gabriel Wardi to explore how artificial intelligence (AI)...
Why do clinicians miss sepsis?
22 Jul 2025
Contributed by Lukas
What if the way we’re trained to recognize sepsis is part of the problem? Nicole sits down with Kathleen Vollman to unpack how clinician education, ...
Is hospital-onset sepsis our blind spot?
15 Jul 2025
Contributed by Lukas
Hospital-onset sepsis presents a complex and urgent challenge at the intersection of healthcare-associated infections (HAIs), antimicrobial resistance...
Can we catch sepsis earlier?
08 Jul 2025
Contributed by Lukas
Can pre-hospital teams catch sepsis before the hospital even sees it coming? Nicole sits down with EMS thought leader Eric Bauer to break down how too...
Can the microbiome predict sepsis?
01 Jul 2025
Contributed by Lukas
Can standard sepsis protocols catch what the gut already knows? In this conversation, Nicole sits down with Dr. Laura Kahn to explore how the microbio...
How are AMR and sepsis connected?
01 Jul 2025
Contributed by Lukas
Unpack the critical links between infection, antimicrobial resistance, and sepsis with host Nicole Kupchik, and learn how together, they’re placing ...
Are microbial mysteries all in vein?
29 Apr 2025
Contributed by Lukas
~ SERIES PREMIERES JUNE 17, 2025 ~ If a microbial mutation falls in a bloodstream forest… does it make a sound? When she’s not pondering wei...