What's next in sepsis? | Season 2 Coming Soon!
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What is the main topic discussed in this episode?
We have evidence where we have information that isn't being well distributed. And that We then see this kind of evolution into shock and multi-organ dysfunction. We feel helpless because we're trying to do the right thing up front, but it ends up that perhaps it exacerbates our patients' injury and illness.
Hi, long time no see. If you're listening or watching on the day this episode's out, today marks the end of Sepsis Awareness Month, which honestly kind of felt like the perfect time to announce the sepsis spectrum is going to be back for season two. I'm really excited for season two, and we're gonna focus on how sepsis affects the lungs and how it affects the kidneys and What could go bad with a GI system? What can happen to our neurologic system? So we're really gonna switch gears and talk about just kind of multi-system dysfunction, because we all know if we stay ahead of the game, we know patients do better. If we can identify deterioration, outcomes are much better. And that brings me to something I am really excited about.
You all know how much I love these fascinating interviews we get to do on the septus spectrum. But in season two, I'm excited to make things a little more two-sided, which means I want to involve you this season. Each episode, I'm gonna read and react to some real-world cases and lived experiences that you have had with multisystem organ dysfunction. So send us your stories. They can be clinical, they can be anonymous, or even personal. Whatever you're comfortable sharing. To submit your stories or experiences, just visit www.human-content.com slash sepsis. Again, that's human-content.com slash sepsis. So recently, around the same time that we're recording this announcement, I sat down with my good friend and Grady Health System Critical Care Clinical Nurse Specialist.
Barb McLean. Barb was recently inducted as a Master of Critical Care Medicine by the Society of Critical Care Medicine for her commitment to critical care worldwide. And I just cannot say how well deserved that designation is to Barb. Because this show is all about sepsis care from various points of view. I wanted to share my own personal experience recently as a patient and how I had to advocate for myself. In addition, Barb and I are going to talk about our decades-long experience with sepsis care and how we've seen things evolve. So let's dive into a few snippets of my conversation with Barbara. I really hope you're going to enjoy this.
What announcement marks the end of Sepsis Awareness Month and the return of The Sepsis Spectrum?
You and I have been doing this a number of decades. And I feel in some ways things have changed quite significantly, but then in other ways, not as much. And if you were to reflect back on your career and what you've seen happen with sepsis, what do you think have been some of the most innovative changes that you've seen?
That's a hard question to answer. So let me first kind of give you my historical view. Uh, I began in critical care nursing in nineteen seventy six, so This next year will be fifty years of clinical practice and as you know, I'm still seeing patients at the bedside. I'm not doing direct care for patients, but I am still in clinical practice. in my hospital and seeing patients and being being a very vocal member of our sepsis committee. Um so I would say that first off would be the recognition of sepsis as its own entity. And for me the Part of the evolution of the understanding of sepsis for me personally was thinking about sepsis as an infection that was overwhelming to recognizing that it was a disorder of the endothelium, to really recognizing that it's an immunity disorder.
and that infection is part of it but isn't the whole of it, that it's actually an immunity disorder. And really that evolution, which I think mirrors the evolution of everybody who works with sepsis, has been Most particularly saying the evolution of appreciation that it's not necessarily the infection. that becomes overwhelming, but the immune response and the dysregulation. And and what that lends itself to kind of in our overview in our clinical practice is
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Chapters
7 chapters
1
What is the main topic discussed in this episode?
0:00–2:58
2
What announcement marks the end of Sepsis Awareness Month and the return of The Sepsis Spectrum?
2:58–8:16
3
How will Season 2 focus on multi‑organ dysfunction and involve listener stories?
8:16–12:09
4
Who is Barbara McLean and what are her major contributions to critical‑care sepsis care?
12:09–16:15
5
What are the most innovative changes in sepsis understanding over the past 50 years?
16:15–19:18
6
How are new biomarkers, rapid pathogen testing, and AI expected to transform early sepsis detection?
19:18–22:34
7
Why is fluid resuscitation shifting away from CVP‑guided protocols toward stroke‑volume‑guided targets?
22:34–23:40