In today's episode, we are diving into NAD+ and exploring how it is a critical component for breaking down fuel, such as glucose, and ultimately converting that fuel to ATP. We will explore various factors that deplete NAD+ or decrease the NAD+/NADH ratio as well as 6 proven strategies to increase NAD+ within the body. Lastly, we wrap up the episode with a conversation pertaining to the use of NAD+ therapy for CIRS/Biotoxin illness, specifically Mold Illness. Thanks so much for tuning it! Topics: 1. Understanding NAD+ and Its Role - Definition of NAD+ and NADH - Explanation of coenzymes in chemical reactions - NAD+ and NADH as coenzymes for electron transfer - Role in glucose metabolism and energy production - Importance of NAD+ for various cellular functions 2. Glycolysis and NAD+ - Illustration of glucose metabolism and insulin release - Role of GLUT4 transporters in glucose entry into cells - Introduction to glycolysis and its steps - Role of NAD+ as a coenzyme in glycolysis - Generation of NADH during glycolysis 3. TCA (Krebs) Cycle and NAD+ - Transition of pyruvate to acetyl-coA - Overview of the krebs cycle and its steps - NAD+ as a coenzyme in the krebs cycle - Accumulation of NADH during the cycle 4. Electron Transport Chain and NADH - Movement of pyruvate into the mitochondria - Role of NADH as an electron donor in the electron transport chain (ETC) - ATP production through the ETC 5. Factors Disrupting NAD+ Balance - Impact of toxins and pesticides on the ETC - Role of drugs, like NSAIDs, in inhibiting the ETC - Generation of reactive oxygen species (ROS) - Role of ROS in mitochondrial damage and NAD+ depletion - Link between NAD+ decline and aging 6. Consequences of NAD+ Depletion - Effect of NAD+ reduction on metabolism - Connection between NAD+ and metabolic diseases - Therapeutic potential of NAD+ in age-related diseases 7. 6 Strategies for NAD+ Restoration - Which supplemental NAD+ precursors are more effective - Inhibition of the CD38 enzyme using dietary nutrients - NAD+ IVs and patches: cost and quality - Intermittent fasting - Exercise and NAD+ - Other less well-known lifestyle factors that have a big impact on NAD+ 8. NAD+ Therapies to Support Recovery from Mold Illness - Link between NAD+ depletion and mold illness - Thoughts on and logic behind the use of NAD+ therapies for CIRS recovery Thanks for tuning in! If you liked this episode, please leave a rating and review or share it to your stories over on Instagram. If you tag @synthesisofwellness, Chloe would love to personally thank you for listening! Follow Chloe on Instagram @synthesisofwellness Follow Chloe on TikTok @chloe_c_porter Visit ⁠synthesisofwellness.com⁠ to purchase products, subscribe to our mailing list, and more! Or visit ⁠linktr.ee/synthesisofwellness⁠ to see all of Chloe's links, schedule a BioPhotonic Scanner consult with Chloe, or support the show! Thanks again for tuning in!

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“What did the council decide on item 42?” — answered with the speaker and the moment.

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