E84: ADHD: Non-Stimulants Part 2: Guanfacine (Intuniv), Clonidine (Kapvay, Onyda XR), TCAs, Bupropion, Solriamfetol, Centanafadine, and Saffron

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Recorded04 May 2026

Publisherfeeds.podcastle.ai

Handlerec:18244524

Show notes

Today we will finish up the medications for ADHD with the remaining non-stimulant medications. There are actually quite a few non-stimulants with more than half being used off label. I will talk about the alpha 2 agonist medications guanfacine and clonidine, which are the FDA approved medications. Then, I will talk about off label options like TCAs and bupropion. Lastly, I will discuss two new medications on the horizon likely to be approved soon, solriamfetol and centanafadine. I will finish with saffron, which is one of the few herbal options which shows some promise.

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