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Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Thyroid Autoimmunity at ThyroLove.com - use code “Podcast” to get 10% off and free shippingThe Investigation I’ve been getting so many questions from my clients and listeners about the various COVID vaccines. I know it can feel like a real mystery, especially if you have an autoimmune issue like Hashimoto’s. I am not an MD but I know you look to me for all types of answers because I can address things from a whole body perspective, explain things in a clear way but also can be unbiased. One of the key questions I get is whether or not someone should get the vaccine. Some have even asked if it’s better to contract COVID 19 as a way to build natural immunity. I unfortunately can’t tell you if you should or should not get the vaccine because I think it’s very personal and the decision is yours and only yours. I am not here to tell you what to do, but my hope is that if I answer your questions and clear up some of the confusion and mystery around it, it will hopefully make the decision, whichever decision you make easier for you. Speaking of which, research on the vaccines is ongoing and new information is coming in each week. This episode was recorded in early May 2021 and refers to the most up to date information at that time. Impact of Symptoms There are a variety of possible responses to both contracting COVID and the vaccine. When it comes to contracting the virus, reactions can range from a few mild symptoms to severe (fatigue, neurological symptoms, headaches, cardiovascular issues, blood clots, or death). These are often exacerbated by underlying conditions. However, research has shown that even those who have minimal symptoms can develop ‘long COVID’ or extended symptoms that last a long time. Research suggests that eating healthy, following a healthy lifestyle, and having sufficient levels of zinc and vitamin D can all lower the severity of the infection and possible symptoms. However, the long term effects are what a lot of people are worried about especially because we don’t know the full extent of them at this time so just getting Covid and “getting it over with” so to speak is certainly not that easy because even if your symptoms are mild, there is a chance for these long term issues and that is not something we want to take lightly. COVID Vaccine Options: What’s the Difference? If you choose to get the vaccine, there are a few options to consider, depending on where you are in the world. There are two main differences between the options: mRNA vaccines and Adenovirus DNA vaccines. Moderna and Pfizer are both mRNA vaccines. Johnson & Johnson (Janssen) and AstraZeneca are DNA vaccines also referred to as adenovirus vector vaccines. COVID Vaccine Options: How do the Vaccines Work? mRNA Vaccines: The Moderna and Pfizer vaccines contain mRNA which code for the spike protein (those are little crowns you can see on the coronavirus when you look at it microscopically). The mRNA itself is very fragile so they have to wrap it in polyethylene glycol which is a lipid nanoparticle. Once that mixture gets into the cells, our cells then read and code it to make the spike protein. Our immune system can then respond by producing B-cells and T-cells. The B-cells produce antibodies so that if we contract COVID, we can fight it off. The T-cells attack and neutralize the virus directly. The difference between the Moderna vaccine and the Pfizer vaccine is in the dosage. Pfizer has 30 micrograms of mRNA while Moderna has 100 micrograms of mRNA. Adenovirus Vaccines: The Johnson & Johnson and the AstraZeneca vaccine are a bit different but they're actually not that much different. These vaccines use an adenovirus (which, by the way, cannot replicate in your cells or mutate) that has DNA injected that codes for the spike protein. The adenovirus gets into our cells, the gene for the spike protein that was inserted into the adenovirus is then read by the cell and copied to mRNA and then the process is the same as the mRNA vaccine so essentially these vaccines are 1 step before the mRNA vaccines and once it becomes mRNA the immune system takes the same steps to create an immune response. It’s important to note that these vaccines are not live viruses and as such, are incapable of viral shedding (as has been falsely shared on social media and websites). More traditional vaccines, like the chickenpox vaccine, for example, may have viral shedding but these COVID vaccines do not. Vaccine Side Effects mRNA Vaccines: With the mRNA vaccines, there are two shots required and it is not uncommon to have side effects. While nobody likes to feel bad, these side effects are not necessarily a bad thing because your body is creating antibodies. When you get the second shot (or booster shot) your body already has these antibodies and they are responding the way they should which is why those symptoms are there and for many people, symptoms don’t typically last longer than a few days. Remember the Moderna vaccine dosage is three times as much as the Pfizer which may be why we are seeing different reactions to the two different mRNA vaccines. I still think it depends on the person and believe that your reaction to the vaccine depends a lot on your immune system. Adenovirus Vaccines: AstraZeneca and the J&J vaccines only require 1 shot so they don’t typically have the same reactions as what people notice after the 2nd shot of the mRNA vaccines however there can be some similar reactions for a few days following the shot. While many people have mild symptoms from either of the vaccines, there are some people, especially those who may be more sensitive, that are noticing extended reactions lasting for more than just a few days and as long as a few weeks or even longer. Some have questions whether the toxins in the vaccines can be causing these but these vaccines are different from traditional vaccines in that they DON’T have heavy metals or formaldehyde. There are other ingredients including polyethylene glycol and polysorbate 80 which, for some people, can create an allergic reaction but another mechanism of action that is not as widely talked about is an immune reaction to the antibodies themselves which brings me to our next and very important question. Vaccine and Autoimmunity There is a possible connection between the vaccine and autoimmune issues. This can happen because of cross reactivity, also referred to as something called molecular mimicry. A study done in January 2021 found that when you make antibodies to the spike protein they can look similar to your own tissues and can cross-react by a process called molecular mimicry. This is very similar to what happens with gluten and Hashimoto's as well as other autoimmune diseases. For example, if your body has an issue with gluten, you would make antibodies to gluten. There are similarities between compounds on the antibodies and on various organs, like your thyroid, for example. So, if your body sees gluten and you have gluten antibodies, it attacks the gluten. And because of the similarities to say your thyroid, it might also attack the thyroid. This is why immunologists and experts are studying the potential cross-reactivity with these vaccines. A study done by Drs Vojdani and Dr. Kharazzian found that the immune system’s response to covid antibodies (which we would get from contracting covid or getting the vaccine as both make antibodies) can be connected to autoimmunity because out of the 50 tissues they tes...