What if the secret to a longer, healthier life isn’t found in a new supplement or a complex medical procedure, but in your cells' own innate ability to "take out the trash"? In this episode, host Eric Verdin is joined by Dr. Ana Maria Cuervo, a pioneer in the biology of aging and professor at the Albert Einstein College of Medicine. The conversation explores the critical roles of proteostasis—the cell's protein quality control factory—and autophagy, the body's natural recycling system. Dr. Cuervo explains her discovery of Chaperone-Mediated Autophagy (CMA) and how keeping these cellular "cleaning crews" active can help prevent neurodegenerative diseases like Alzheimer’s and Parkinson’s. The episode concludes with actionable insights into how sleep, exercise, and meal timing can naturally jumpstart these longevity-promoting pathways.Ana Maria Cuervo is a Spanish-American physician, researcher, and cell biologist. She is a professor in developmental and molecular biology, anatomy and structural biology, and medicine and co-director of the Institute for Aging Studies at the Albert Einstein College of Medicine. She is best known for her research work on autophagy, the process by which cells recycle waste products, and its changes in aging and age-related diseases.Support the show

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