Brady Holmer
speaker
932 appearances
3 recordings
1 series
first heard Jun 2026
last heard 29 Jul
Brady Holmer’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 3 in all, peaking in Jun 2026 with 2.
Appearances
We're seeing these benefits.
They're experiencing less overreaching symptoms.
They are improving their work output capacity after overtraining.
But it was like, what the hell's going on?
We don't know the mechanism by which this this is working 'cause they didn't really they measured it what did they measure in that study?
It was like FGF twenty one or
Some molecule messages.
Yeah, it was some inflammator inflamm inflammatory biomarker marker, and that was the only thing they measured.
Like this might be a novel over training biomarker.
Um and I've seen that actually in some uh some recent studies too, the FGF twenty-one.
I think I'm getting that uh
that molecule right, but that was like the only mechanism that they kind of proposed.
So this is sort of following up on that.
And we actually do have some mechanisms.
So, you know, you mentioned ET one, endothelin one, PGC one alpha.
Um, can we talk a little bit about those in terms of like the mechanisms by which these effects might be happening?
Yeah, and even in I mean, even with something like PG C one alpha or AMPK, you know
You might expect like 24 to 48 hours out.
Again, maybe they don't have these time points in the study, so it would be fascinating to have like a 24 hour, 48-hour follow-up.
But to see those happening in six hours is is really cool to see that signal.
Showing 561–580 of 932 · page 29 of 47
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