David Fagenbaum

But there are tangible things we can do.

But I think it all starts at

reflecting on what are you hoping for, what are you wishing for, and I think that's a great place to start with what you should be doing every day.

That's right.

I've realized there's this circuit, and it all starts with hope.

You know, what are you hoping for?

And that hope really needs to drive action.

And if that hope drives action, what I've found is it often will drive impact.

And well, what does impact do?

It gives you more things to be hopeful for.

It gives you more hope.

You can create this incredible circuit.

Hope, action, impact leads to more hope, action, impact.

And all of a sudden, years later, you're sitting here with these two amazing people and all of you and able to share about an organization every year that's saving lives of patients all over the world.

But it all starts with that first hope and turns to action and impact.

Sure, I'm happy to start.

Yeah, absolutely.

So many of us in this room have received medicines for diseases that they're not approved for to treat us.

It's called off-label use.

In fact,