Derek (More Plates More Dates)

So getting in front of it, the only thing like how they developed these drugs was they found that individuals that had a mutation in the gene that encodes for 5-alpha reductase seemed to not undergo full sexual maturation in adolescence and they would end up with

Shockingly, the same amount of muscle mass as like, you know, they're like, for example, siblings who weren't affected, but inhibited maturation of genitals, for example, like not full that often end up with like a micro penis.

It's like where that comes from typically.

But also no facial hair growth, really, and no temporal recession is like one of the hallmarks of, you know, the they're called pseudo hermaphrodites, which is like, I don't know, male pseudo hermaphrodites.

And maybe that's not like a correct term now, but that's what they are in the literature.

And it is literally... These individuals have no inhibition in their capacity to produce testosterone.

It is all the DHT.

Now, it doesn't mean that testosterone doesn't also have a similar effect on hair follicles.

It's just the magnitude of effect is so much less that if you get in front of it, like, you know, day one, unless you're highly susceptible, the inhibition via...

inhibiting that enzyme is likely going to be sufficient to offset loss visibly for your entire life because it's a progressive thing.

And you won't even notice the cosmetic difference in hair density until you've lost like 25 plus percent of your hair.

So like if I pull a hair out of my head right now,

Visibly, it would look no different.

If I pulled two hairs on my head, it would look visibly no different.

But once you start to get to like tens of thousands of hair follicles that you have on average, depending on the ethnicity, but like, I think it's like 70 to like 80,000, upwards of 100,000 hair follicles on your head.

Once you've gotten to the point that you're down like 10,000, 20,000, 30,000, all of a sudden you're starting to see visibly like in downlight and you can see through your scalp and you couldn't before.

You're starting to see yourself in pictures and you're like, that's weird.

Like, I don't remember seeing...

I have to, like, part my hair weird now to cover this spot.

Like, what the hell's going on?