Dr. Abe Malkin
speaker
151 appearances
1 recordings
1 series
first heard Nov 2024
last heard Nov 2024
Dr. Abe Malkin’s voice in public audio — every appearance, attributed to the second.
Trend
recordings per month · last 12 monthsNo recordings in the last 12 months.Older appearances are listed below; set an alert to hear about the next one.
Appearances
Where can people find those in the archives? Those archives? I think they would be very entertaining.
Pleasure. See, this is what happened. You put me on the podcast. I learned all your trade secrets and I just went out and started my own business.
Yeah, what's interesting is this is a new product, the Niagen IV, that is basically a precursor to NAD. If we were getting an NAD IV right now, we would both be so uncomfortable. We wouldn't be able to do the podcast. I think we actually tried to do it at one point and we just couldn't do it.
Do you remember? Yes. And you need to be like a professional athlete to get through it quickly. And the Niagen IV is much different. It gives you even more benefit than the NAD IV, but you can race through it in 75% faster than you can an NAD IV. So we're going to get the IV done in 30 or so minutes. Really helps with energy, with mood, with sleep, with brain health.
So a lot of benefits of the IV in a very short amount of time.
Those in the biohacking community have known about NAD for a long time, but it's great that now it's becoming more mainstream. Makes my job a lot easier that I don't have to explain it to as many people because people are starting to hear about it now from their friends, their doctors, and so forth. But essentially, NAD is an enzyme, a coenzyme, that helps your body generate chemical reactions.
So everything you do in the world requires your body to be generating chemical reactions. And you burn through your NAD levels. And as you age, you produce less and less NAD, which is one of the reasons that contributes to aging.
so from an anti-aging perspective nad is really helpful for helping reverse the clock so as you're performing these chemical reactions your body is using up the nad almost like a blank check so whether you need more energy or better sleep you have addiction problems or whatnot nad is really giving your body what it needs through that chemical reaction process it's
powering your energy production in your mitochondria. So at a very basic level, as you age and your body requires more and more NAD, repleting it with IVs or orally can really help you give yourself the stuff it needs to help prepare itself.
Great question. So NAD is made up of two things, made up of NR and NMN. And so a lot of people are out there selling NR supplements, selling NMN supplements. NAD is the combination of two. But the reason you hear about NAD specifically with IVs is that it's not bioavailable. So if you take it orally, you can't absorb it into the cells, which is why you have NR and NMN supplements.
So with this IV in particular that we're getting right now, because it's NR, it can pass through directly into our cells without having to get broken down first. Which is why when you get an NAD IV, it takes three hours because you have to infuse it, it gets broken down, it's uncomfortable, and then it's absorbed up into the cells.
Whereas the Niagen IV with NR is absorbed directly into the cells as you infuse it.
So there's been studies on both sides, NR and NMN, about the bioavailability and effectiveness. I think there's studies on both sides, but it's clearly evident that NR is absorbed into the cell directly, whereas NAD has to be broken down into the two components. And that's why you see supplements selling oral NR or NMN. You won't see supplements selling oral NAD.
would say that the literature at this point is pointing to nr being more effective and more absorbed better absorbed into the cell and leading to higher levels of nad and really ultimately that's what you're trying to get you're trying to get higher levels of nad so what's really important is to actually track your increase in nad levels to get an objective measurement and that's what's exciting right now a lot of people have been talking about the subjective benefits of nad for years
Better energy, better sleep, better mood. But now there are tests coming out which can objectively measure your NAD levels after taking supplementation, either orally or via IV.
I would say the hierarchy in terms of effectiveness and absorption is the best way you can take any supplement for that matter is really IV because that gets completely absorbed into the cell, then intramuscular or subcutaneous, and then oral. And so the amount of NAD... gain you can generate from a treatment via IV is far greater than what you can gain via oral.
If you had to take oral pills to equal the amount of NAD that you're getting from an IV infusion, you'd have to take many, many pills, and that just wouldn't feel good in your stomach. So for most people, the amount of NAD delivered via IV is far greater than an oral pill, which is why you generally see better absorption rates via IV. Can you OD? No, that's a great question.
You asked me the other day, you said, hey, I just got an iGen IV the other day. Can I have another one today? It's like putting gasoline in your car or getting an oil change. Your car will run more efficiently if you get an oil change every day, but you can't have too many oil changes. And so I say to people, your body will use up whatever you give it.
You're constantly performing chemical reactions and using up NAD. So the more you give yourself, the better it will run.
It's a molecule that your body is constantly using it. So you will use NAD on a several day lag time. So if you get an IV today, you'll use it up over the next two or three days. You're not going to use it up all right away, but your body will use more of it the more you give it. And so it is soluble. So if you do, you could essentially urinate it out.
Showing 1–20 of 151 · page 1 of 8
Next →