Dr. Cara McDonald

Mm-hmm.

But it's probably not a significant factor because the inside of your body does not get a whole lot hotter than it normally does.

So, you know, there is a possibility of becoming resistant, much like when we have a vaccination or we've had a virus and then we actually build immunity to that virus.

You can build immunity to the neurotoxin molecule.

And there are some brands that claim you're less likely to get resistance with one brand than another.

But again, there's no good evidence for that at this stage.

The rates of resistance are very low.

It's thought to be less than half a percent of people that have it for cosmetic reasons.

It actually goes up.

in those people that are having it for medical reasons because they are having much, much higher doses of the drug.

And that seems to increase your chance of resistance a little bit.

And the frequency of having your injection.

So if you have them too frequently or very high doses, that potentially increases your chance a little bit.

And once you're resistant, then there's not a lot you can do about it.

Yeah, you can't really swap from product to product because it's similar.

Same drug.

Unfortunately, nothing proven, nothing known.

I think that, you know, we would all like to think that there was something we could do to change it, but no one has really worked it out yet.

But what we do see is that for those people where it wears off faster and

They see a fairly standard duration every time, but sometimes switching to a different brand and there are some brands that give increased longevity in those where it wears off.