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Dr. Casey Means

๐Ÿ‘ค Speaker
1139 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

And I don't think the dose on ginseng has been settled, but very high antioxidant component plant.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

When we look at actually stimulating more GLP-1, you've talked about your Ramate, I think, having like a mild effect on GLP-1.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

But there's actually a lot of other things in the literature.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

Protein, of course, very potently stimulates these nutrient receptor cells.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

And specifically like valine and glutamine seem to have a potent stimulatory effect on GLP-1.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

So you're going to find that in like meat and turkey and eggs and things like that.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

Antioxidants, lowering blood sugar, ginseng.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

So those are kind of the L-cell ones.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

The actual secretion of more GLP-1

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

one of the most potent ones, and the study that looks at this, like the bar graphs are very clearly statistically significant, lots of asterisks, is actually thylakoids.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

Thylakoids are so fascinating.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

Thylakoids are actually a structure in plants

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

that are part of the chloroplasts.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

So, you know, chloroplasts, and this also is fasting because chloroplasts are basically the plant version of mitochondria, essentially.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

And thylakoids are a molecule in the chloroplasts.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

And there's actually been research that shows that when you eat about 100 grams of spinach, which gives you 5...

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

grams of straight thylakoid over 12 weeks daily, it led to a significant increase in GLP-1.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

And again, I don't remember the exact... It was two or three-fold higher secretion.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

So this is in part... So that's a direct stimulatory effect of the L-cells.

Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation

And so this equates to 3.5 ounces of spinach a day, which is like nothing.