Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
And I don't think the dose on ginseng has been settled, but very high antioxidant component plant.
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
When we look at actually stimulating more GLP-1, you've talked about your Ramate, I think, having like a mild effect on GLP-1.
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
But there's actually a lot of other things in the literature.
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
Protein, of course, very potently stimulates these nutrient receptor cells.
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
And specifically like valine and glutamine seem to have a potent stimulatory effect on GLP-1.
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
So you're going to find that in like meat and turkey and eggs and things like that.
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
Antioxidants, lowering blood sugar, ginseng.
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
So those are kind of the L-cell ones.
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
The actual secretion of more GLP-1
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
one of the most potent ones, and the study that looks at this, like the bar graphs are very clearly statistically significant, lots of asterisks, is actually thylakoids.
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
Thylakoids are so fascinating.
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
Thylakoids are actually a structure in plants
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
that are part of the chloroplasts.
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
So, you know, chloroplasts, and this also is fasting because chloroplasts are basically the plant version of mitochondria, essentially.
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
And thylakoids are a molecule in the chloroplasts.
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
And there's actually been research that shows that when you eat about 100 grams of spinach, which gives you 5...
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
grams of straight thylakoid over 12 weeks daily, it led to a significant increase in GLP-1.
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
And again, I don't remember the exact... It was two or three-fold higher secretion.
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
So this is in part... So that's a direct stimulatory effect of the L-cells.
Huberman Lab
Dr. Casey Means: Transform Your Health by Improving Metabolism, Hormone & Blood Sugar Regulation
And so this equates to 3.5 ounces of spinach a day, which is like nothing.