Dr. Craig Koniver
speaker
302 appearances
1 recordings
1 series
first heard Oct 2024
last heard Oct 2024
Dr. Craig Koniver’s voice in public audio — every appearance, attributed to the second.
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Appearances
They are actually. You can use- Sorry, my mistake. Yeah. So I think that using the term stem cell is a problem, right? If we use the term autologous cell, right, which would be PRP, it's basically the same thing. Platelet-rich plasma. Right. They take your blood, they spin it down, they take the- Right. And so the ruling is, I understand it. As long as you're taking a cell from you,
Sure.
Yeah, no, and I think, like anything, there's going to be people who get too aggressive. I've heard of doctors injecting stem cells into people's discs, and then they get discitis, an infection, and that can just spiral very quickly. I think you've got to be reasonable in what you're trying to accomplish.
I'm excited about stem cells and exosome therapy and PRP and PRF and using them as, you know, kind of biologics because I think there's a lot to learn. I think we only know very little from what we've seen from working with our patients. It's been tremendous from a rejuvenation standpoint.
Yeah, I think it was, from my observation, the best peptide for immune modulation. So we would use it if you had an overactive immune system, like autoimmune disease. By definition, if someone has an autoimmune disease, their immune system is attacking their own self, right? That's classically lupus, rheumatoid arthritis, things like that, celiac disease, type 1 diabetes.
Those are all autoimmune diseases. We could use thymus and alpha-1, and we'd tone down the immune response. We'd also use it a lot in post-COVID, where you have an abnormal immune response or the immune system hasn't caught back up and you can kind of dial it up using thymus and alpha one in a very simple use a lot with long COVID.
And we were using 5,000 micrograms a day, sometimes intravenously, getting great results, very safe, had no issues with it. But unfortunately, it's off the table.
Yeah, it made the cut.
That's right. We've used a lot of Cerebral Lysine. I actually have a clinic that's open in London. We actually did use it. We've used it a lot more over there than over here. So you have a U.S. clinic and a U.K. clinic. We have one based in London and one in Charleston, yeah. Okay. And I think cerebral isin has been used for decades in the setting of post-stroke, post-traumatic brain injury.
The trouble with it, again, I've observed with people They get cerebral isin. We're talking about IV. You can also use it sub-Q. Is they will have a day or two where they feel really down and out. Like it's like their mood shifts to like this dark place. Scary. Yeah. And they come out of it. But most people don't like that feeling. And so we just, we stopped using it mostly. Yeah.
Yeah. And I think, right. And I think, I think collectively it increases BDNF levels, right? Like there was dihexa too. You know, if you're familiar with dihexa, that's another one that was removed by the FDA. Supposedly the most potent way to increase, you know, brain-derived nootrophic factor is kind of the juice the neurons live in again, oversimplification. that's gone.
But I think cerebral isin did the same thing. Interesting.
It does for sure. Not permanently. Not permanently. It's actually the first... pharmaceutical ever prescribed in this country in the late 1800 was methylene blue. Goodness. Here. So it sounds like really renegade, but it's not. Got it. Yep. But it's it's gained favor in the last five years.
That's certainly when we learned about it, particularly, you know, I learned about it through this doctor who was telling me with COVID patients he was getting immediate, like within a day of stopping of COVID symptoms from using methylene blue. That's what like piqued my interest. Like, wow, that's incredible.
And then he went on to say that then COVID tests were turning negative within a matter of like two days, which was unheard of. I've seen that with something else, but I'll get back to that. And so that's when I was like, oh, this is, you know, it started to be talked about and learned about it.
So methylene blue, when we talk about the mitochondria using that mitochondrial membrane binds to cytochrome C oxidase. And I think of it, you know, traditionally it's used when people have carbon monoxide poisoning. They'll still use it. You go in the emergency room, you have carbon monoxide poisoning, it'll give you methylene blue.
And it helps your red blood cells displace the carbon monoxide and put oxygen there. And so it's an oxygenator. That's how I think of it.
Yeah, I don't believe it's on the water list. Okay. I don't believe. Or just look for the people with the blue tongues. Yeah, easy test. So methylene blue, absorbed very well orally. I think of it like NAD, the molecule NAD, because it works on those cytochromes. Different than NAD, though, because NAD is not, if you're taking NAD by itself, not absorbed orally well at all.
It's one of the trouble with it. Methylene blue is, and actually you can take way bigger dosages orally than intravenously. We've given it intravenously a lot, but we're limited in using it intravenously just because it'll start to cause some spasm of the vein. The arm starts hurting if you're giving too much methylene blue, either too much or too quickly. And so we can give it orally.
You can get a capsule of it. That's how we, our pharmacy- What dosages? So I think a good dose is no more than 10 milligrams. 10 milligrams. Yeah. Taken when? In the morning. It is, you know, it's a cognitive stimulant for sure.
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