Dr. Craig Koniver
speaker
302 appearances
1 recordings
1 series
first heard Oct 2024
last heard Oct 2024
Dr. Craig Koniver’s voice in public audio — every appearance, attributed to the second.
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And what we found is as long as people are losing less, two pounds or less a week, they're they're not losing the muscle mass.
We certainly encourage adequate protein intake, you know, resistance training, but that microdosing has been a game changer, like literally a game changer because then people don't feel like, and I've seen it where when we started, people were losing, you know, 15 pounds in three weeks. Goodness. Right? And then they're like excited.
But then they're not because then they come off of it and they just gain it right back. Or they lose a lot of weight and they lose that fat in their face and they look like skeletons. We've seen those called ozempic face. We don't like the way that looks. And that fat takes a while to come back. So if we just go slowly with this and we can really dial it in and nuance it,
That has had a tremendous impact. And now, beyond the weight loss, you know, we're seeing cognitive benefits. We're seeing, you know, inflammation benefits. A lot of people with autoimmune disease who their inflammation markers are coming down, and that's the only thing we can think is working.
Great question. Or I could say, is it the positive thoughts that come from looking at yourself in the mirror and feeling good? which transcends to feeling better about yourself, and that feeds forward to the momentum that you put forth in the world, all of those things. I think it's all of the above. I think that's going to be hard to dissect, but it's real. I mean, I have a patient, she's 50.
She has Hashimoto's thyroiditis, meaning she attacks her thyroid. She doesn't make enough thyroid hormones, so she takes thyroid hormone. Well, one of the challenges with that is they make a lot of thyroid antibodies, this antibody called thyroid peroxidase antibody. And when you have an elevated thyroid peroxidase antibody, you don't feel good. You feel inflamed, your joints hurt, you get rashes.
Life is just not easy. And it's a challenge to get that number down. I mean, it's certainly a challenge for me. You traditionally use probiotics, a lot of things to help bolster the immune system. Well, now we're starting to use the GLP-1s and we're seeing that those antibody levels come down. And I don't have a great way of explaining it, but there's something going on that's very positive.
So many. So I think with BPC, for me, kind of the most utilized peptide that we've used. So we'd like to use BPC almost with every patient. It is very anti-inflammatory. And so just from a very general perspective, most people walking around who are adults, they're stiff, they're sore as they get older, they work out. We work with athletes of all levels. There's that element of inflammation.
Maybe they have some chronic disease, diabetes, heart disease, autoimmune disease. Inflammation is paramount, we understand that. And BPC, I've observed with so many patients, we're talking thousands upon thousands of patients, where their inflammation comes down, so they feel better, they're not as stiff, they're not as sore, their knee doesn't hurt as much, their shoulder's improved.
So we've learned, you know, that we start with a dose, you know, based upon these, like you said, animal studies, which is conservative, make sure it's safe. And then we've seen over time that we can get to higher and higher dosages and have even more of an impact, you know. And I think so for people understanding using BPC, we started with a dose of like 500 micrograms a day.
We got up to 5,000 micrograms a day, you know, and we'd like a protocol five days on, two days off. And that's been very helpful for a variety of things from post-viral, you know, with the pandemic. Had a lot of success with BPC to, again, you name it.
Honestly, almost everyone I could think of, particularly as people are engaging more fitness-related lives, they're working out more, I would argue that anyone who's working out on a regular basis, BPC is going to benefit. It's going to help, you know, improve the inflammatory status but also help with recovery. And it doesn't seem to be one of these agents that's going to be detrimental.
Like we were talking earlier, Rob and I, for the starter, like, you know, they found that people are working out hard taking antioxidants. There seems to be a negative consequence to that because you don't allow the body to kind of repair itself. I don't think that's happening with BPC.
It does, right. And so it works well if you're, you know, we'll get into taking a growth hormone-releasing peptide. It pairs very well with that because then you're working both sides of the equation, meaning if you're using a growth hormone-releasing peptide like semirelin or ipramirelin, GHRP6, whatever, you're helping your pituitary put out more growth hormone.
Well, if you combine it with BPC, which upregulates the growth hormone receptor, you make the process of growth hormone binding more efficient. So you get more out of it. Then you can use less of the growth hormone-releasing peptide with the same result.
I think it can. What we've observed is it's more limited to the gut. So people with any sort of gastrointestinal issue, whether that's inflammatory bowel disease like Crohn's or ulcerative colitis, irritable bowel, you name it, leaky gut, I think oral BPC is more effective there. Has it been shown to be effective for those conditions or have you observed that clinically?
I've certainly observed that clinically. But interestingly, I've observed a better clinical response when people inject it.
even for gastrointestinal related things so i think injecting and then so people injecting subq which is right under the skin we use the tiniest of needles like an insulin needle 30 or 31 gauge we're talking super small um and so i know a lot of people like i'm never injecting yeah this is less painful than a um than a texas mosquito bite there you go super easy once you do it once or twice it's really easy and we walk people how to do how to do that but interestingly i we started thinking okay if you've got something going on your gut you should take oral ppc because it's going to target it right then and i found
Now, if we're injecting, it actually works better than the oral. And then it came up, well, what if I've got an elbow injury? Should I inject it in my elbow? And we found actually don't. It's going to work systemically. You can inject it in your abdomen or your rear end.
You're still going to get benefit in your elbow, but now you're going to get benefit in all your joints, all over your body systemically.
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