Dr. David Allison
speaker
936 appearances
1 recordings
1 series
first heard Mar 2026
last heard 31 Mar
Dr. David Allison’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 1 in all, peaking in Mar 2026 with 1.
Appearances
And so that's something we need to keep in mind.
Now there will be other times when there are situations, even if the drug causes exactly a five kilo weight loss, let us just suppose for the moment that you were exactly five kilos above the threshold for obesity.
And I was not, I was 10 kilos above the threshold for obesity.
Now we express the outcome as, did it make you obese or not obese?
It made you go from obese to not obese.
It made me go from obese to still obese.
Same weight loss, different outcome by measuring things differently.
So now when you think of other thresholds, the threshold to have a heart attack, right?
It could be that something lowers my LDL cholesterol exactly the same amount as it lowers your LDL cholesterol.
But my LDL cholesterol had me up at the threshold of about to get a heart attack.
Your LDL cholesterol, let's say, was not at that threshold.
So it rescued me from the heart attack.
It didn't rescue you.
I think there's different levels of knowledge.
And as I said, I use the example of myself.
One of my heuristics, not my only one, but one of my heuristics is if the FDA has said this pharmaceutical for people like me is reasonably safe and it's effective, that's usually good enough for me to judge.
to make the judgment that for someone like me, it's effective and reasonably safe.
Safety is a social judgment.
Effectiveness is not.
Effectiveness is empirical judgment.
Showing 541–560 of 936 · page 28 of 47
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