Dr. Jonathan Schoeff

speaker

2,131 appearances 2 recordings 1 series first heard Jul 2026 last heard 28 Jul

Dr. Jonathan Schoeff’s voice in public audio — every appearance, attributed to the second.

Trend

recordings per month · last 12 months

Recordings per month over the last 12 months — 2 in all, peaking in Jul 2026 with 2.

Appearances

newest first · ▶ plays the moment

Habits and Hustle · Episode 575: Dr. Jonathan Schoeff: Peptides and the Marketing Behind Modern Longevity - Part 2 · 28 Jul 2026 podcast

It's terrible.

It's as close as you come to having a heart attack and a respiratory thing if you really open it wide.

So bear in mind what you're feeling systemically

is very minimal to intracellular levels.

NAD and NAD+, NADH, they're an electron donor in the mitochondria.

So that's inside a cell.

So NAD in your bloodstream is irrelevant.

has to be in the cell nad cannot readily cross through a cell membrane into the cell there's no clear carrier so you probably get some ultra small percentage meaning we have to give you a big slug of nad to get a little bit in your cell so i think what you're feeling and experiencing is largely the circulatory effects of nad

But what matters from a longevity perspective, because NAD does two things.

Again, it aids in the electron transport chain energy, you know, fuel to energy.

And, but the other piece is it's a co-factor in the DNA mismatch repair system, which is literally our bodies.

It's wild.

So every time a cell splits, you literally do copy your entire DNA to a new cell.

So imagine as you age, that process keeps happening more room for error.

but we have a built-in system called the the dna mismatch repair system that nad is a powerful cofactor that goes through literally this is what makes the human body wild goes through and checks our entire genome before that cell gets the okay

really yeah that's how so that's where nad so that's kind of that longevity energy piece so nr so then then we talk about so that's that's what nad does in the cell okay the the tragedy is in the bloodstream doesn't count so the it's actually the precursors that establish the highest level of intracellular concentration so what you're saying in our nicotinamide riboside

There's some mixed data.

NR and NMN are the two precursors that are used commonly.

I'm a bigger advocate for NR.

I think there's more compelling data that NR is readily transported into the cell.

Showing 981–1000 of 2,131 · page 50 of 107