Dr. Karan Rajan

speaker

2,601 appearances 14 recordings 1 series first heard May 2026 last heard 7 Sep

Dr. Karan Rajan’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 14 in all, peaking in Jun 2026 with 5.

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Dr Karan Explores · Weight Loss Surgeon: Why Exercise and Calorie Cutting Doesn’t Work | Dr Andrew Jenkinson · 20 Jul 2026 podcast

feel the satiation level so much.

We don't feel the fullness signals as much as maybe we used to before we, you know, mutated the environment to such a degree.

On that note, now that you've got this set point and people struggling with, you know, weight loss and who are obese have that leptin resistance, how can someone begin to shift away from that leptin resistance and

Move the needle on their weight set point.

Yeah, I mean, going back to what I was mentioning, a personal anecdote of mine when I was cycling through periods of weight gain and weight loss and i it felt almost suffocating because I couldn't get out of this vicious cycle.

So I do empathize with a lot of people going through that.

And, you know, I think the most clarity I've found in weight loss and sustaining it has come over the last couple of years where, you know, I adhered to a lot of the things that we've discussed already, where I did start cooking

Cooking my own meals, like the bulk of my meals cooking that.

And actually, you know, I do snack every now and then, and for context, probably this is the slowest but most sustained weight loss I've had.

I've lost fifteen kilos over two years, which is like a slow methodical weight loss, and it it's stuck with me.

Oh wait.

And you know, I guess that also allows you to just subtly nudge your set point just a tiny bit instead of making huge

Huge fluctuations in the thermostat and turning it down and turning it up.

And one of the things there was actually more fiber, more protein, but actually being quite calculative with the timing.

So I would have most of my fiber and protein and most of my calories earlier in the day, when my digestive function is at its peak, so timing it with my natural circadian clock, and I would attach

attenuate or decrease slowly the number of calories I'd have as I got later in the day as my digestive prowess decreased.

So I'd probably have only a few hundred calories in the afternoon and evening.

And importantly, I'd stop eating at least three or four hours before bed.

So maybe about six or seven PM I'd have my last meal.

And then I'd have my breakfast at 10 or 11 o'clock in the morning.

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