Dr. Kyle Gillett

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556 appearances 2 recordings 1 series first heard Dec 2025 last heard 2 Jul

Dr. Kyle Gillett’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 2 in all, peaking in Jul 2026 with 1.

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Huberman Lab · Essentials: Tools for Hormone Optimization in Males | Dr. Kyle Gillett · 2 Jul 2026 podcast

So even if your androgen receptor sensitivity doesn't change, and even if your testosterone does not change, you will have more testosterone binding to that increased number of receptors.

Does one need to cycle L-carnitine, creatine, betaine?

No reason to cycle any of those.

Let's briefly mention vitamin D, which is also a hormone.

It's actually a sterile hormone.

And if you have deficient vitamin D and you replace it, then you will optimize your testosterone.

Let's also mention boron.

So if you have a very high SHBG, boron can acutely help lower it, usually in a dose of five to 12 milligrams per day.

It's not really a sustained effect, but boron is depleted in soils.

In many countries, I believe it's very high in soils in Greece and Turkey.

So eating dates or raisins that are from those areas potentially have more boron.

Boron also might be one of the reasons why the reference range for testosterone is much higher in those countries.

than other countries.

We can talk about things that affect the steroidogenesis cascade.

So we could touch on Tongkat Ali.

I know we've talked about that a little bit before.

Yeah, but I'm guessing a number of people probably haven't heard that conversation.

also known as long jack, and that upregulates several different enzymes in this steroidogenesis cascade.

And by that, what you mean if, and this is another good thing to Google, I think anybody interested in hormone optimization should understand where sterol hormones come from.

They come usually from cholesterol and they can be shunted off to vitamin D very easily.

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