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Dr. Kyle Gillett

๐Ÿ‘ค Speaker
308 total appearances

Appearances Over Time

Podcast Appearances

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

So DHT helps a lot for the same reason why testosterone helps.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

It helps effort feel good.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

So it can be motivating.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

There's lots of dietary changes and supplementation that you're probably doing right now that's affecting your DHT.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

You mean me personally?

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

Well, everybody, all of the listeners.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

Because let's say you have a diet high in plant polyphenols.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

Many of those inhibit the enzyme that converts testosterone to DHT.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

Yeah, turmeric, black pepper extract.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

Do you recommend that people avoid curcumin and turmeric for that reason?

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

If someone's DHT is already low or if they have somewhat insensitive androgen receptor,

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

via genetics or via lifestyle, then I recommend they avoid bioavailable curcuminoids like bioavailable turmeric, black pepper extract.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

You want some sort of strategy to decrease the activity of that androgen receptor.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

There's a lot of different things that you can do that are topical.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

The most promising is called dutasteride mesotherapy.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

Essentially what it is is it's very localized injections in areas that are prone to male pattern baldness, whether they're female or male, and it acts locally only.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

and you repeat these injections from time to time, it decreases the conversion of testosterone to DHT just in the scalp.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

Yeah.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

So PCOS is polycystic ovarian syndrome.

Huberman Lab
Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

And this is one of those conditions which is