Dr. Mike Roberts

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1,217 appearances 1 recordings 1 series first heard Jul 2026 last heard 8 Jul

Dr. Mike Roberts’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 1 in all, peaking in Jul 2026 with 1.

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Perform with Dr. Andy Galpin · What Drives Muscle Growth & What Doesn't | Dr. Mike Roberts · 8 Jul 2026 podcast

You can do this in a Petri dish.

He found a way to get mitochondria into cardiomyocytes to see if that mitigated any of the bad response to hypertrophy.

What we want to do, and I've told Nick this clearly, is what happens if we take muscle cells in a Petri dish, we transplant mitochondria into those muscle cells, we have another bucket of cells that we do like a vehicle, so no transplant, and then we give them both an anabolic stimulus.

Does that added mitochondria lead to enhanced hypertrophy?

Because that is an unsolved question.

One would be capillary-

Because enhanced capillarization or the enhancement of the network of capillaries with endurance training also occurs.

We're not even touching that in this conversation, which leads to enhanced perfusion, et cetera.

And then with that, the other hallmark adaptation is the reticulum expansion of the mitochondria.

So in the human model, it's tough to disentangle.

Was it capillary?

Was it mitochondria?

Was it both?

Was it something we didn't even look at?

I hate like writing just in vitro only papers, but I told Nick,

this would be the perfect one because we're clamping all that.

We're removing that from the equation.

Let's give these guys more mitochondria in the Petri dish versus not, and let's hit them with IGF-1.

And if we see an enhancement in MPS, like muscle protein synthesis, and an enhancement in cellular hypertrophy...

then that's probably the best evidence that we have that, hey, look, those older individuals I told you earlier in our conversation that are deconditioned and they see this robust increase in mitochondrial biogenesis with resistance exercise, that could be part of the driving force.

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