Dr. Nathan Bryan

speaker
1,178 appearances 5 recordings 3 series first heard Feb 2025 last heard 3 Apr

Dr. Nathan Bryan’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 3 in all, peaking in Apr 2026 with 1.

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So the foods we eat, and I'm sure we'll address that, that are enriched in nitrate, the bacteria in and on the body convert that into nitrite and nitric oxide. So that obviously is dependent upon our diet. It's dependent upon the oral microbiome, and it's dependent upon stomach acid production. Any of those steps become compromised, and we lose the ability to make nitric oxide.
So one can compensate for the other. If we have poor endothelial function, if we eat a certain diet, we support the microbiome, and we have stomach acid, you can kind of compensate, if you will, for the lack of endothelial function.
But if you have endothelial dysfunction, a poor diet, and that's what most Americans are faced with, we see poor health, metabolic disease, hypertension, sexual dysfunction, cognition decline, and eventually Alzheimer's.
So just by way of clarification, we're ranking it based on overall health or overall nitric oxide production.
So these may be really bad for you, but it may be completely independent of nitric oxide production. Okay. So there may be a disconnect there. Okay, okay. Poor sleep is probably the worst thing. It would certainly be an F. But is it because it's disrupting nitric oxide production? If that were the case, then I would have to rank it probably midway, kind of halfway in between.
But certainly, poor sleep is a driver of chronic disease.
Yeah, so stress is one of these subjective things that you ask, right? But for stress, for me, there's a stress response. There's stress hormones. There's overproduction of cortical. There's overactivation of the sympathetic nervous system and dysautonomia. And so what we have to do is correct that stress response. And so, but this is, you know, this takes...
a mental kind of a complete change in perspective. You know, everybody's stressed. We live in a stressful world, but stress doesn't solve anything. And I made a conscious decision many years ago that if I can't change it or control it, then I don't worry about it. And think about that. If you can't change the situation or control the situation, you shouldn't worry about it.
That's 99% of the things that people stress over. Right. So what I do is it's, and it's still saying, it's not what happens to you that matters. It's how you respond to what happens to you that matters. So, You know, I live a pretty stress-free life.
People apply a lot of stress to me. I just don't stress over it because if I can't control it or change it, what good does it do? It's not going to change the situation. No, but what we have to do is affect the, you know, there's something called adrenal fatigue and the adrenal glands secrete these things like adrenaline, these stress hormones and cortisol.
So when you have an elevation, chronic elevation of cortisol, I mean, that's a normal stress response. We need that acutely. But when you're chronically stressed, then it completely shuts down and disturbs other hormones and the whole endocrine system.
And it'll eventually shut down nitric oxide production because you're inflamed, you develop oxidative stress, and you develop an immune dysfunction.
Yeah, we call that hormesis in terms of how the body adapts to, because when we exercise or when we go for a run or when we do a cold plunge, it's an acute stress on the body. So the body then transduces an adaptive response. So like resistance training, there's intermittent hypoxia when we contract our muscles. It's squeezing on the blood supply. and then it's causing intermittent hypoxia.
So the body responds with angiogenesis. We're creating more blood vessels. So now with that same resistance, we're not developing hypoxia because now we revascularize that tissue. We develop, you know, we build more protein, we build more muscle, and that's, you know, the benefits of weight training.
For instance, when we run, you know, if you're doing a marathon and you're running for two to three hours, you're completely diverting blood flow away from the kidneys, the intestines, and some people can develop ischemic organ disease. But the body adapts to that and go, oh, I don't want to run out of oxygen again. I need more mitochondria. Turns on mitochondrial biogenesis.
It improves the oxygen utilization. So now that cell can make more energy with less oxygen. And why is that? Because it was confronted, it dealt with a stress, an acute stress. And that's kind of like the cold plunge. When I go from the sauna, 170 degrees to 37 degrees, it's flexing the blood vessels. Because when you're hot in a sauna, your blood vessels are maximally dilated.
trying to rid the body of the heat so it doesn't overheat. Then when you go to cold, the body's trying to preserve heat so it constricts all the blood vessels. But for me, it's like weight training for your blood vessels because there's smooth muscle that's around all the blood vessels and it's working them out. But it's stressful. But the adaptive effects to that acute stress
Well, we have to move. I mean, humans are designed to be mobile, to move. And yet most Americans aren't. We get in our car, we drive to work, we sit for six, eight, ten hours a day. Nobody gets exercise. And then the calories we consume through diet are stored as fat and become unhealthy.
But we have to move and kind of scientifically explaining this because exercise has been shown to stimulate nitric oxide production. And that's why exercise is medicine. You're giving your body activation and stimulation of nitric oxide. The other thing is kind of an electrical, you know, we're electrical beings, right? We diagnose death through loss of electrical activity, EEG or EKG.
So we have to maintain electrical conductance and flow and current and maintain voltage across cell membranes. Muscles are what we call piezoelectric, meaning that when we contract muscles and we move muscle, they're muscle battery packs. So they're creating voltage. And through the fascia, through these meridians, those muscle battery packs supply different organs with certain voltage.
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