Dr. Nathan Bryan
speaker
1,178 appearances
5 recordings
3 series
first heard Feb 2025
last heard 3 Apr
Dr. Nathan Bryan’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 3 in all, peaking in Apr 2026 with 1.
Appearances
But, you know, we can use this mouth rinse. Sure. And we'll just do a little demo here.
And now test strip. So obviously we've diluted the saliva a little bit, right? So maybe give it a couple seconds. But, you know, mine didn't. Mine was already pretty optimal. But what we're finding is that if what we've done with this mouth rinse, we can now start to see a complete change in the microbiome. Yeah. And what we're finding is kind of the same. The same.
So again, this takes time. Right. Because the turnover of these bacteria.
Because the target for me was. Dysbiosis. In dental medicine, we need to still address the pathogens. The pathogens may be causing systemic disease. The oral pathogens causing systemic disease. We still need to address those. So how do we selectively kill the pathogens? But how do we restore and improve the diversity of the non-pathogenic commensal oral bacteria?
That's been the target, and that's what we've accomplished with this toothpaste and with the mouth rinse. That's exciting. All right.
The ones that I know that are probably the best clinically validated is a device called the Endopat. Endopat, sorry. Endopat, yeah.
So, and then there's others, you know, there's a CV profiler, there's the max pulse, all these, but they're all doing different things. The endopat is what we're looking, it's called flow mediated dilatation and it's venous occlusion plethysography is kind of the technique. But what that device does is, if you've done it, they put a blood pressure cuff on your brachial artery. Yep.
And then they pump it up to suprasystolic levels to where it's completely impeding blood flow.
Yeah, so for five minutes. So your fingers will tingle because there's no blood flow. Yeah. For five minutes. And then they release the cuff, and now you're getting this oxygen-starved tissue. It's now getting blood flow. The body's natural response is reactive hyperemia.
So the hypoxic, the low oxygen environment, when you release the cuff, if you have good endothelial function and the endothelial cells can make nitric oxide, it immediately dilates the blood vessels. It immediately produces nitric oxide and immediately dilates the blood vessels.
So in the endopat, I believe they're looking at change in temperature of the fingertip, which is correlated to how well, how fast the blood supply returns to that ischemic tissue.
Yeah.
Now that's the functional production of nitric oxide because nitric oxide is produced. It's gone in less than a second. It signals, it relaxes the smooth muscle, dilates the blood vessels. And that's the only way you can detect it. What we're doing here is kind of understanding the circuitry and the oxidative end products of nitric oxide and how the body handles it.
But then there's other machines that are non-ischemic or non-occlusive that's looking at the elasticity of the blood vessels or the compliance of the blood vessels. So with each beat of the heart, you know, the aorta is very important because it dampens that pulse response.
And the ability of the endothelial cells to produce nitric oxide to dampen that heartbeat and that pulse response predicts vascular health.
Because if you have stiff arteries with each beat of the heart, that pulse wave travels really fast down the vascular tree. Then when it hits kind of the bifurcation at your renal arteries, that wave reflects. Now you've got a reflective wave going on that new heartbeat, and there's an overlap, and you can look at the waveform.
on that and so that's the beauty of things like the cv profile or the max pulse because it's looking at the structure of the blood vessels if somebody's listening today and they're like well i want to find a practitioner that does these tests where do they go look there's not enough clinicians i mean the really good innovative physicians cardiologists like dr twyman mark houston the ones that are kind of on the cutting edge of diagnostics and clinical care
You got to find them. But as we, and the beauty of this podcast is if patients go to their doctor and demand this and they start asking enough, then they'll almost be forced to bring it in the clinic. And there's no reason they should, because whether it's a cash practice or an insurance-based practice, there's ICD-10 codes for these diagnostics.
The data is only good if you know what to do with it and how to interpret it.
Well, I mean, sunlight is beneficial in many ways. Part of it is due to the release or activation of nitric oxide. So there's certain wavelengths of the sun, both infrared and both ultraviolet, so kind of both ends of the visible light spectrum. So infrared light coming from the sun or infrared light technology provides a frequency and a vibration that can release nitric oxide bound to metals.
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