Dr. Robert Lustig
speaker
405 appearances
4 recordings
4 series
first heard Dec 2024
last heard 12 Jan
Dr. Robert Lustig’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 1 in all, peaking in Jan 2026 with 1.
Appearances
You still get an insulin response. And the more other food you ate, the bigger the insulin response. So you will have an accentuated insulin response because you're exposed to the diet sweetener. This is work from Yanina Pepino, 2013 at Wash U St. Louis. And it's been corroborated multiple times since.
Because insulin's a bad guy. So we always talk about glucose being a bad guy in terms of diabetes, and it is, of course. But insulin's a bad guy too. Glucose causes small vessels... to be dysfunctional, causes endothelial cell dysfunction. It causes high blood pressure because it causes those small vessels to constrict.
It interferes with nitric oxide, which is one of the things that relaxes the blood vessel. and it will basically reduce blood flow to specific organs. So high glucose is not good for you, and it's bad for small vessel disease. And that's why diabetics get retinopathy, nephropathy, neuropathy, kidney disease, nerve damage, and eye disease.
But insulin is also a problem because what insulin does is it causes cell growth. Insulin is a growth factor and it causes vascular smooth muscle growth like in your coronary arteries and it causes glandular growth. So it is one of the primary drivers of heart disease and cancer.
So you can be a diabetic, a type 2 diabetic, and have your hemoglobin A1C, a measure of your glucose control, down near normal range because you're on insulin or oral hypoglycemics or even GLP-1 analogs for that matter, okay? And you will die just the same because you will die of a heart attack or of a cancer because diabetics have a much higher incidence of cancer.
They also have a higher incidence of dementia as well. And the reason is because of insulin because insulin is a bad guy in this story. Glucose causes microvascular disease. The insulin causes macrovascular disease. They're both bad. You need to control both of them. And this controls the glucose. It doesn't control the insulin.
So the other thing that we've learned about non-nutritive sweeteners across the board is that they alter the microbiome. Now, the microbiome is the bacteria that live in your gut. Now, you have to feed your microbiome. You have to feed your bacteria. Because if you don't feed your bacteria, your bacteria will feed on you.
It will strip the mucin layer, a protective physical barrier, right off the surface of your intestinal epithelial cells. And when it does that, it denudes them and allows for other bacteria, toxic bacteria, to take up residence and cause irritable bacteria. bowel syndrome, inflammatory bowel disease, and the junctions between the cells become dysfunctional as well.
And so the cells become permeable. And so stuff in your intestine, the junk in your intestine, the SH, you know what? can actually make it through into the bloodstream. You can measure the endotoxins and the whole bacteria, the lipopolysaccharides in the bloodstream when the intestine is damaged even from diet soda. And what that does is that ultimately leads to systemic inflammation.
And that systemic inflammation also leads to metabolic disease, mental health problems, cognitive decline, early death.
sort of tooth comb over every single thing that they're putting into their body they're not a scientist agreed it's a it's a problem because the food industry has made the grocery store a minefield and it's really easy to set off an explosion if you walk in you've basically lost that's how bad it is understood so the the simple rule is eat real food So what's real food?
Well, food that came out of the ground or animals that ate food that came out of the ground. The problem is we all lead busy lives and we're looking for labor-saving devices because people don't even have time to cook. Most people, 33% of Americans don't even know how to cook anymore. So, like, what are they going to do? So we understand this. I mean, it's a problem. Agreed.
We need food that is metabolically healthy for us, not metabolically detrimental. And the problem is that as soon as you put added sugar in the food, you have made it metabolically detrimental. Now, the food industry will say, well, there are all these other good things in there, like vitamins and minerals. We fortify it, et cetera.
So I'm here to tell you, toxin A plus antidote B still equals death. Just because they put some vitamins in there or you take a dietary supplement, if it's not solving your mitochondrial dysfunction, what's the point? So you can't believe what the food industry is telling you. If they say something is healthy, it's usually the opposite. Whatever it says on the package, believe the opposite.
Because they have an incentive to put... Wrong stuff on the package. And I'll be honest with you, I'm part of, you know, numerous lawsuits suing the food industry for deceptive advertising, misbranding, mislabeling. 70% of all of the items in the American grocery store are misbranded or mislabeled. In what way? They say things that are not true. Give me some examples.
Well, first of all, any time they use the word healthy... They say no added sugar, but in fact they put in apple puree or raspberry puree or evaporated cane juice. There are 262 names for sugar, and the food industry uses all of them. And so they will say that something's no added sugar, but that in fact is actually not the case. Okay, there's a whole host of this.
Kellogg's has been sued for raisin bran. Okay, everyone thinks raisin bran. Well, it's just raisins and bran. What color are the raisins in raisin bran? I've never seen it. Well, I mean, raisins are purple.
You know, purple brown.
Yeah, normally. Well, the raisins in Raisin Bran are white. Why? If you take the raisins in Raisin Bran, that's supposed to be 11 grams of sugar, but on the side of the package, it says that one serving is 18 grams of sugar. Where'd the other seven come from? It's the white. Because they've all been dipped in a sugar solution to make them sweeter. As an example. Okay?
So, Post has been sued, General Mills, theirs was dismissed. Mondelez, a whole host of companies are actually under the gun now to change their practices. Why do you care so much? I am a pediatrician. My job is to take care of children. Children are vulnerable in the same way minorities are vulnerable, in the same way prisoners are vulnerable, okay? They need a voice.
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