Erin Allman‑Updyke and Erin Welsh
speaker
988 appearances
1 recordings
1 series
first heard Aug 2026
last heard 4 Aug
Erin Allman‑Updyke and Erin Welsh’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 1 in all, peaking in Aug 2026 with 1.
Appearances
25 of them compared to only four diet trials, compared to only two at the time on PCSK9 inhibitors, which I'll get to in a second.
Right.
One on ezetimibe, which is another medicine that we use.
And so what that means is not only do we have so much data on their effect, it also means that our confidence intervals on just exactly how effective they are are really narrow for statins.
Right.
So we know, without a doubt, that statins are extremely effective at lowering our LDL cholesterol and at reducing the risk of adverse cardiovascular events, period.
What did that study show, the meta-analysis show, in terms of by the numbers impact?
So by the numbers, statins are the most consistent.
Diet has a slightly less effect, but still a significant effect.
PCSK9s, which I'll get to in a second, have the greatest effect.
They lower LDL cholesterol the most and they reduce your risk the most.
But the confidence intervals are super wide because at least at that time, we just didn't have as much data on them.
Right, right.
Yeah.
And then the other ones are in between.
But statins are like...
Pound for pound, I guess.
I don't know if that's right, but like incredibly effective and like just so much good data to support them.
Right.
We're really dialed in on how statins work and how well they work.
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