Erin Allman‑Updyke and Erin Welsh
speaker
988 appearances
1 recordings
1 series
first heard Aug 2026
last heard 4 Aug
Erin Allman‑Updyke and Erin Welsh’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 1 in all, peaking in Aug 2026 with 1.
Appearances
we dramatically reduce, not just like a little bit do we reduce how much cholesterol your liver is making, you're dramatically reducing, like putting a huge break on how much cholesterol your liver can make.
And because all of our cells still need cholesterol,
Our cells have to get better at taking cholesterol out of our bloodstream.
So they actually upregulate those LDL receptors, those Velcro sticky hands on the surface of their cells that capture our LDL cholesterol floating around in our bloodstream.
So it's not just that, oh, we're not making as much cholesterol.
It's that we're not making as much cholesterol and our body cells still need cholesterol.
So they start vacuuming it out of our bloodstream at really high rates.
Isn't that cool?
Oh, yeah.
I love that.
There's also some interesting evidence that statins also might have a little bit of like an anti-inflammatory effect as well.
Yeah.
inflammation is an integral part of that.
And so there's some thought that there's also an anti-inflammatory effect of statins, though we don't fully understand that mechanism there.
So that's how statins work.
And they're incredibly effective, Erin.
There was a meta-analysis from 2016 that was really interesting.
So it's kind of old now, but it looked at over 50 different studies that looked at all the different possible interventions that we had at that time and all of the randomized control trials of those different interventions and the effect of lowering LDL cholesterol on cardiovascular disease risk by these different interventions, okay?
Mm-hmm.
We had 25 trials on statins.
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