Erin Allman‑Updyke and Erin Welsh (This Podcast Will Kill You hosts) - primarily Erin Allman‑Updyke or Erin Welsh
speaker
917 appearances
1 recordings
1 series
first heard Jul 2026
last heard 28 Jul
Erin Allman‑Updyke and Erin Welsh (This Podcast Will Kill You hosts) - primarily Erin Allman‑Updyke or Erin Welsh’s voice in public audio — every appearance, attributed to the second.
Trend
recordings per month · last 12 monthsRecordings per month over the last 12 months — 1 in all, peaking in Jul 2026 with 1.
Appearances
Yes.
Yes.
I was like, can that be us?
I want that to be us.
I don't think we'll ever create something as good as Rogers and Hammerstein, though.
Let's be real.
But Brown and Goldstein, they were fascinated by the mystery of familial hypercholesterolemia, and they wanted to figure out what caused such high levels of LDL in the blood in affected individuals, because that was really one of the key features of this was high LDL.
As they discovered, it wasn't that there was too much LDL being produced.
It was that too little LDL was being taken up by the cells.
I love this so much, Darren.
So the cells of people with familial hypercholesterolemia lacked receptors that would allow them to scoop up the LDL from the bloodstream.
So they didn't have those little Velcro hands.
Right.
They didn't have enough Velcro hands.
Right.
And so LDL just kept piling up, piling up, circulating and circulating with nowhere to go.
And over time, it just, again, it's a numbers game.
It's going to lodge into the blood vessel walls.
It's going to cause a blockage, inflammation, plaques, et cetera, et cetera.
Huh.
Showing 821–840 of 917 · page 42 of 46
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