Jason Karlawish
speaker
1,378 appearances
5 recordings
1 series
first heard Feb 2021
last heard Dec 2023
Jason Karlawish’s voice in public audio — every appearance, attributed to the second.
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Appearances
The net compendious benefit of this drug to patients.
And the kind of conversations that we're gonna have are conversations about, well, is it about lowering amyloid quickly early on?
And then stopping the drug and following amyloid levels?
Is it about a persistent lowering of amyloid that you have to s uh keep people on the drug?
Is it about lowering amyloid and also seeing tau go down and following tau?
All these things are gonna be part of the conversation in the next twenty-four months, two, three years.
And this is how I think the thinking about this disease.
From the perspective of pharmacologic treatment is going to change the way we talk about the disease.
And I think our profession needs to be part of that conversation.
Needs to be
Talking that language, understanding the way we talk about that language, and contributing our expertise and wisdom to interpreting the data, both to understand its benefits to patients, but also how to help patients understand it and families understand.
Because I think we're uniquely good as a profession with taking care of patients and helping them understand risks, benefits, and uh and and and balancing those with their other diseases, et cetera.
So that's why I'm
pro for this drug entering the clinic and for our profession being prescribers for it.
every seventy years the Cubs make it to the World Series.
it
So so infusion every two weeks, that's a personal choice as well as obviously thinking through the benefits and the risks, particularly for people who are Apo E four carriers.
Um but let me jump to very point.
You asked uh you mentioned patient quality of life.
Actually, among the secondary endpoints in the study was um uh the Zarat rating of caregiver burden.
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