Jason Karlawish
speaker
1,378 appearances
5 recordings
1 series
first heard Feb 2021
last heard Dec 2023
Jason Karlawish’s voice in public audio — every appearance, attributed to the second.
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pounded with cognitive testing and monitoring.
If
Doing fine.
I think considerations of uh of of saying, Well, you've got Alzheimer's el elevated amyloid
I think that the
Matters of cultural and social uh stigmas should be thought about.
But if someone showed me
that an intervention in those individuals could change the natural history of decline, I'd say, look, we're just gonna have to work through those stigmas because I've got some way to alter that natural history.
And indeed, as we saw with HIV, there's certainly still a stigma that surrounds HIV, but the ability to treat HIV very much transformed the nature of what it is like to have that disease.
And we can go through any number of diseases where that's the case.
Mental illnesses, et cetera.
I'm not saying they're stigma-free.
I'm not, but these will be ongoing cultural conversations.
I guess I'm just sticking to the sort of position that.
I would like someday to be able to diagnose Alzheimer's as well as Louis body disease, et cetera, before someone has disabling impairments.
I would.
Absolutely.
But I don't think that right now the science says that elevated amyloid alone is the label Alzheimer's.
Which engenders the notion that it's a valid construct.
I don't think the construct has been validated.
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